News tagged with target genes
Infectious disease may have shaped human origins, study says
Roughly 100,000 years ago, human evolution reached a mysterious bottleneck: Our ancestors had been reduced to perhaps five to ten thousand individuals living in Africa. In time, "behaviorally modern" humans ...
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Jarid2 may break the Polycomb silence
Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a ...
Apr 30, 2012 |
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Red wine, fruit compound could help block fat cell formation
(PhysOrg.com) -- A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential ...
Apr 04, 2012 |
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Scientists design nano-sized drug transporter to fight disease
Scientists seeking to improve cancer treatments have created a tiny drug transporter that maximizes its ability to silence damaging genes by finding the equivalent of an expressway into a target cell.
Nanotechnology / Bio & Medicine
Jul 26, 2011 |
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New drugs target delay of Huntington's symptoms
(Medical Xpress) -- McMaster researchers have discovered a new drug target that may be effective at preventing the onset of Huntington's disease, working much the same way heart medications slow the progression of heart disease ...
May 31, 2011 |
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In Parkinson's disease, brain cells abandon mitochondria
In a study that sheds new light on the causes of Parkinson's disease, researchers report that brain cells in Parkinson's patients abandon their energy-producing machinery, the mitochondria. A shutdown in fuel can have devastating ...
Medicine & Health / Medical research
Oct 06, 2010 |
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Newly identified RNA sequence is key in microRNA processing
Researchers at Tufts University School of Medicine and Tufts Medical Center have identified an RNA sequence that promotes increased numbers of specific microRNAs (miRNAs), molecules that regulate cell growth, development, ...
Aug 16, 2010 |
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We are not only eating 'materials', we are also eating 'information'
In a new study, Chen-Yu Zhang's group at Nanjing university present a rather striking finding that plant miRNAs could make into the host blood and tissues via the route of food-intake. Moreover, once inside the host, they ...
Sep 19, 2011 |
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Single-molecule technique captures calcium sensor calmodulin in action
It's well known that the protein calmodulin specifically targets and steers the activities of hundreds of other proteins - mostly kinases - in our cells, thus playing a role in physiologically important processes ...
Aug 10, 2009 |
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Rare variants in gene coding may up risk of autoimmune disorders
(PhysOrg.com) -- Rare variants in the gene coding of an enzyme that controls the activity of a key immune cell occur more often in people with autoimmune disorders like rheumatoid arthritis and type 1 diabetes, ...
Jul 01, 2010 |
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Molding the business end of neurotoxins
For snakes, spiders, and other venomous creatures, the "business end," or active part, of a toxin is the area on the surface of a protein that is most likely to undergo rapid evolution in response to environmental constraints, ...
Feb 23, 2012 |
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Pack 'Em In -- Gold Nanoparticles Improve Gene Regulation
Investigators at Northwestern University have found that packing small interfering RNA (siRNA) molecules onto the surface of a gold nanoparticle can protect siRNAs from degradation and increase their ability to regulate genes ...
Nanotechnology / Bio & Medicine
Feb 23, 2009 |
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UCSF creates fast, affordable tool for finding gene 'on-off' switches
UCSF scientists have created a method of quickly identifying large numbers of the genetic material known as short hairpin RNA — also called shRNA - that turns genes on and off.
May 19, 2009 |
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Scientists work with RNA silencing and plant stem cells
Research on controlling the stem cells of plants could eventually lead to learning how to make them produce more fruit, seed and leaves, according to Dr. Xiuren Zhang, Texas AgriLife Research scientist and professor with ...
May 16, 2011 |
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Scientists uncover a genetic switch that turns immune responses on and off
Scientists are keeping their eye on a new discovery published in the November 2011 print issue of the FASEB Journal that explains what causes some genes to go out of control. Scientists have identified a "cellular switch ...
Nov 01, 2010 |
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