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Biochemistry news

Researchers assemble library of sugars

Sugar structures called GAGs are present in almost all tissues in the human body, and have important functions in various diseases. The understanding of these sugar structures is limited, because tools to study them have ...

dateAug 15, 2018 in Biochemistry
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Mapping the inner workings of a living cell

Imaging tools like X-rays and MRI have revolutionized medicine by giving doctors a close up view of the brain and other vital organs in living, breathing people. Now, Columbia University researchers report a new way to zoom ...

dateAug 06, 2018 in Biochemistry
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New method refines cell sample analysis

Researchers at the University of Zurich have developed a novel method for analyzing cells and their components called iterative indirect immunofluorescence imaging (4i). This innovation greatly refines the standard immunofluorescence ...

dateAug 03, 2018 in Biochemistry
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Cryo-electron microscopy characterizes integrins

A collaboration between three labs at UC San Francisco has resulted in an unprecedented look at a member of a vital and ubiquitous class of proteins called integrins (pronounced "INT-uh-grins"). Integrins are associated with ...

dateJul 31, 2018 in Biochemistry
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Researchers find new way to target flu virus

There's a hitch in the swing of a protein that delivers the flu virus. Rice University and Baylor College of Medicine researchers believe this mechanism may be a useful target to stop the virus from infecting cells.

dateJul 24, 2018 in Biochemistry
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Fueling the MATE transporter

Evolutionarily conserved transport proteins, such as those belonging to the multidrug and toxic compound extrusion (MATE) superfamily, protect cells against toxic chemicals and contribute to multidrug resistance in cancer ...

Chemists characterize the fatal fungus among us

Life-threatening fungal infections affect more than two million people worldwide. Effective antifungal medications are very limited. Until now, one of the major challenges is that the fungal cell wall is poorly understood, ...

Infrared sensor as new method for drug discovery

Using an infrared sensor, biophysicists at Ruhr-Universität Bochum (RUB) have succeeded in analysing quickly and easily which active agents affect the structure of proteins and how long that effect lasts. Thus, Prof Dr. ...

Protecting ribosome genes to prevent aging

Aging is a process of gradual deterioration from exposure to time and the elements; this process begins with deterioration deep inside every cell. Researchers from Stanford University and the VA Palo Alto Health Care System ...

The secret sulfate code that lets the bad Tau in

Vampires can turn humans into vampires, but to enter a human's house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how ...

Bioengineers create pathway to personalized medicine

Engineering cellular biology, minus the actual cell, is a growing area of interest in biotechnology and synthetic biology. It's known as cell-free protein synthesis, or CFPS, and it has potential to provide sustainable ways ...

New computational method for drug discovery

HITS researchers developed tauRAMD, a tool to predict drug-target residence times from short simulations. The method is illustrated on the cover page of July 2018 issue of the Journal of Chemical Theory and Computation, software ...

Discovery of new type of antibiotic

A new type of antibiotic may help millions of COPD patients and children with middle ear infections. The drug is unlikely to have any side effects and has the great advantage that no resistance development can occur. Researchers ...

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