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The natural antibiotic lugdunin, discovered three years ago by Tübingen researchers, attacks pathogenic bacteria in several different ways simultaneously. It also interacts with the defense mechanisms of the human body, ...
Biochemistry
1 hour ago
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Mycophenolic acid (MPA), discovered in 1893, was the first natural antibiotic to be isolated and crystallized in human history. Today, this fungal metabolite has been developed into multiple first-line immunosuppressive drugs ...
Biochemistry
Jun 21, 2019
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Mortierella alpina lives in the soil and likes to keep cool. This fungus, which belongs to the zygomycetes, grows best at temperatures of 10 to 15 degrees C and occurs mainly in alpine or arctic habitats. In biotechnology, ...
Biochemistry
Jun 21, 2019
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A team of researchers from McMaster University has mapped at atomic resolution a toxic protein linked to Alzheimer's disease, allowing them to better understand what is happening deep within the brain during the earliest ...
Biochemistry
Jun 20, 2019
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The sweet, starchy orange sweet potatoes are tasty and nutritious ingredients for fries, casseroles and pies. Although humans have been cultivating sweet potatoes for thousands of years, scientists still don't know much about ...
Biochemistry
Jun 19, 2019
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Sigma receptors are proteins found mainly on the surface of endoplasmic reticulum (ER) in certain cells. Sigma-1 and sigma-2 are the two main classes of these receptors. The sigma-1 receptor is involved in neurological disorders ...
Biochemistry
Jun 19, 2019
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The main constituents of cells, tissue, organs, and whole organisms are proteins, which are built by the addition of amino acids one after another to form long protein chains called polypeptides. Although living cells have ...
Biochemistry
Jun 18, 2019
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DNA may have appeared on Earth earlier than has hitherto been assumed. LMU chemists led by Oliver Trapp show that a simple reaction pathway could have given rise to DNA subunits on the early Earth.
Biochemistry
Jun 18, 2019
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The mysterious function of a key protein has been revealed following a breakthrough by University of Dundee scientists.
Biochemistry
Jun 17, 2019
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One of the main challenges of second-generation biofuel production is identifying enzymes produced by microorganisms for use in a cocktail of enzymes to catalyze biomass hydrolysis in which the enzymes act together to break ...
Biochemistry
Jun 17, 2019
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It's a feat three decades in the making: Harvard University chemists have achieved what a new paper calls a "landmark in drug discovery" with the total synthesis of halichondrin. Known to be a potent anti-cancer agent in ...
Biochemistry
Jun 17, 2019
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Scientists in Japan have developed a way of amplifying DNA on a scale suitable for use in the emerging fields of DNA-based computing and molecular robotics. By enabling highly sensitive nucleic acid detection, their method ...
Biochemistry
Jun 14, 2019
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The human cytochrome P450 enzymes are responsible for metabolizing a variety of substances—from lipids (fats) and steroid hormones to drugs and toxic chemicals.
Biochemistry
Jun 14, 2019
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Antibiotics save countless human lives—modern medicine without them is unimaginable. The largest proportion by volume of industrially produced antibiotics today are cephalosporins, structural variants of the first antibiotic, ...
Biochemistry
Jun 14, 2019
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A recent study published in the April 8 issue of Nature Chemical Biology improves on the "Cellular Reprogramming" method developed by Nobel Laureate in Medicine and Physiology Prof. Shinya Yamanaka, making it possible to ...
Biochemistry
Jun 13, 2019
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A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...
Biochemistry
Jun 13, 2019
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Queen's University researcher P. Andrew Evans has uncovered a new process to deliver antibiotics using pollen to shield them.
Biochemistry
Jun 13, 2019
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Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport ...
Biochemistry
Jun 13, 2019
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Noroviruses are a leading cause of food-borne illness outbreaks, accounting for 58% of all outbreaks and cause 685 million cases worldwide each year. There is no effective therapeutic against them. Having knowledge of the ...
Biochemistry
Jun 12, 2019
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Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now ...
Biochemistry
Jun 12, 2019
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