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Frozen hydrogen cyanide 'cobwebs' offer clues to origin of life

A substance poisonous to humans—hydrogen cyanide—may have helped create the seeds of life on Earth. At cold temperatures, hydrogen cyanide forms crystals. And, according to computer models reported in ACS Central Science, ...

A protein found in the GI tract can neutralize many bacteria

The mucosal surfaces that line the body are embedded with defensive molecules that help keep microbes from causing inflammation and infections. Among these molecules are lectins—proteins that recognize microbes and other ...

Scientists boost mitochondria to burn more calories

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic ...

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Biochemistry
New technique lights up where drugs go in the body, cell by cell
Biochemistry
Electricity-driven nitrogen insertion enables sustainable heterocycle synthesis
Biochemistry
Engineered enzyme turns formaldehyde pollutant into key pharmaceutical building block
Biochemistry
Rare earth elements: Of peptides and the origins of life
Biochemistry
A new natural sunscreen: Novel compound discovered in thermophilic cyanobacteria
Biochemistry
Enzyme shape-shifting captured in real time during catalysis
Biochemistry
Improved tracer labeling expands PET imaging possibilities
Biochemistry
Light-controlled cholesterol 'look-alikes' point toward smarter drug delivery
Biochemistry
Accelerating next-generation drug discovery with click-based construction of PROTACs
Biochemistry
Quantum mechanical molecular 'fingerprints' solve machine learning mystery
Biochemistry
Chemists develop unique tool for studying RNA in live cells
Biochemistry
Enzyme disables bacterial toxin by cleaving key chemical ring structure
Biochemistry
Your body is full of medicine. Researchers can now synthesize it
Biochemistry
Vital intertwining: Blood parasite's chainmail-like DNA structure could inspire next-generation materials
Biochemistry
New method enables precise fluorine addition to drug-like molecules in one step
Biochemistry
Composite copper oxides show strong, long-lasting antiviral action against tough viruses
Biochemistry
Synthetic key enzyme enables the conversion of CO₂ into formic acid
Biochemistry
Study uncovers new drug target for huge class of viruses
Biochemistry
Biphenomycin biosynthetic pathway decoded, opening door to new antibiotic development
Biochemistry
Simulation may illuminate safer cannabinoid drugs

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Plants & Animals
A shark's energy reserves are linked to how far it travels, suggests new study
Plants & Animals
Scientists uncover hidden 'winter memory' inside plants
Molecular & Computational biology
All ears: New study pinpoints what determines ear length in dogs
Plants & Animals
'Supercooling' keeps salamanders from freezing in Canadian winters
Archaeology
Humans returned to British Isles earlier than previously thought at the end of the last Ice Age
Earth Sciences
3D mapping of fault beneath Marmara Sea reveals likely sites for future earthquakes
Plants & Animals
Austrian cow shows first case of flexible, multi-purpose tool use in cattle
Astronomy
X-ray observations reveal hidden disturbances in galaxy cluster Abell 3571
Bio & Medicine
A new nanorobot designed to improve immune cell recognition could help treat colorectal cancer
Earth Sciences
Wildfires trigger massive soil loss for decades, new global map shows
Condensed Matter
Quantum 'alchemy' made feasible with excitons
Plants & Animals
Marine wildlife rarely interact with tidal turbines—and usually avoid collisions when they do, observations show
Earth Sciences
Calm seas can drive coral bleaching, research reveals
Earth Sciences
Japan Trench geology confirmed as key driver of 2011 megaquake
Analytical Chemistry
COVID-era trick could transform drug and chemical discovery
Plants & Animals
Seychelles leads the way in the protection of sharks and rays, finds study
General Physics
Observing the positronium beam as a quantum matter wave for the first time
Environment
AI helps reveal global surge in floating algae
Astrobiology
Experiments bring Enceladus' subsurface ocean into the lab
Space Exploration
How to prevent charge buildup in a lunar rover

Chemists develop unique tool for studying RNA in live cells

An innovative three-color method for capturing images of mRNA inside live mammalian cells has been developed by UMass Amherst chemists. Because RNA is both incredibly important to human life and health and poorly understood, ...

Study uncovers new drug target for huge class of viruses

A study from the University of Maryland, Baltimore County (UMBC), published in Nature Communications, reveals how enteroviruses—including pathogens that cause polio, encephalitis, myocarditis, and the common cold—initiate ...

Simulation may illuminate safer cannabinoid drugs

New psychoactive substances, originally developed as potential analgesics but abandoned due to adverse side effects, may still have pharmaceutical value if researchers could nail down the causes of those side effects. A ...