Related topics: genes · cells · protein · genome · cancer cells

Revealing branching time in single-cell omics data

New single-cell omics technology allows scientists to analyse cell development in ways that were not previously possible. Researchers can now identify never-before-seen patterns and phenomena across large quantities of cells—receiving ...

A model to decipher the complexity of gene regulation

How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...

Sex and diet affect protein machineries

Scientists from EMBL Heidelberg have discovered that the collection of proteins in an animal cell—called the proteome—is substantially affected by both the animal's sex and its diet. Understanding these individual proteomes ...

Turning an old enemy into a helpful friend

Half our genome is basically foreign, derived from viruses. Obviously, the invasion of such foreign elements can deregulate critical biological processes, and lead to disease. This is why animals, including humans have evolved ...

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as rRNA genes or tRNA genes, the product is a functional RNA.

Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.

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