Related topics: genes · cells · protein · genome · cancer cells

Scientists teach old worms new tricks

Model organisms such as yeast, fruit flies, and worms have advanced the study of genomics, eukaryotic biology, and evolution. An important resource for any model organism is a near-complete reference genome from which a multitude ...

Researchers create most complete model of complex protein machinery

Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the ...

Revealing branching time in single-cell omics data

New single-cell omics technology allows scientists to analyse cell development in ways that were not previously possible. Researchers can now identify never-before-seen patterns and phenomena across large quantities of cells—receiving ...

A model to decipher the complexity of gene regulation

How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as rRNA genes or tRNA genes, the product is a functional RNA.

Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.

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