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Scientists upturn understanding of how key hormones act in cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related ...

Testis-specific gene involved in sex ratio regulation discovered

Although enormous progress has been made over the past few decades in genetics, molecular biology and biochemistry, the ways in which living beings orchestrate their internal processes at the microscopic scale is still full ...

Researchers find fat burning molecule in mice

Linked to serious health problems including cancer, diabetes and cardiovascular disease, obesity affects more than a third of adults in the United States. Presently, there are few safe and effective nonsurgical therapeutic ...

Cholera strain becomes unexpectedly resistant to infection by phages

Graduate student Kristen LeGault and assistant professor Kimberley Seed, both in the Department of Plant and Microbial Biology, specialize in the evolution of human pathogens and the viruses that infect bacteria, known as ...

Mapping of genetic control elements in the cerebellum

The mammalian cerebellum has long been associated almost exclusively with motor control, yet recent studies indicate that it also contributes to many higher brain functions. An international research team led by Prof. Dr. ...

Differentiating strong antibiotic producers from weaker ones

An untapped trove of desirable drug-like molecules is hidden in the genomes of Streptomyces bacteria—the same bacteria responsible for the first bacterial antibiotics to treat tuberculosis back in the 1940s.

How ERF1 regulates flowering

Floral initiation must be strictly regulated to achieve reproductive success. ETHYLENE RESPONSE FACTOR1 (ERF1) functions as an important integrator of several phytohormone signals to regulate both development and stress responses. ...

Small proteins discovered to be regulators of the aging process

Scientists have discovered that the protein ubiquitin plays an important role in the regulation of the aging process. Ubiquitin was previously known to control processes such as signal transduction and metabolism. Prof. Dr. ...

Exploring blood types of Neanderthal and Denisovan individuals

An analysis of the blood types of one Denisovan and three Neanderthal individuals has uncovered new clues to the evolutionary history, health, and vulnerabilities of their populations. Silvana Condemi of the Centre National ...

Molecular atlas reveals how brain cells develop

As the fertilized egg divides, initially undifferentiated cells take on specific functions, becoming more distinct as different tissues and organs emerge. Understanding how hundreds of disparate cell types arise has proven ...

Double-strand RNA exhibits traits different from single-stranded RNA

Messenger RNA, or mRNA, has been in the news recently as a crucial component of the Pfizer-BioNTech and Moderna COVID-19 vaccines. The nucleic acid looks, for all intents and purposes, like a strand of DNA that has been sliced ...

Developing probiotic beverages without animal protein

Most products enriched with probiotics and protein are made with dairy products. However, consumer demand for plant protein is growing. The nutritional value of these proteins must therefore be improved to be comparable to ...

Want to reduce cockroach sex? Block an enzyme

It's not the look in her compound eyes or the shape of her carapace that really attracts the male cockroach to his mate. Instead, it's all those 29-carbon hydrocarbons in her cuticle that drive him wild. How the female cockroach ...

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First-ever gene expression map of an entire nervous system completed
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Giant amoeba-infecting viruses rely on DNA-packing proteins
Evolution
Genomic secrets of gutless deep-sea tubeworm unlocked
Plants & Animals
New study sheds light on function of sex chromosomes in turtles
Biotechnology
Researchers discover that protein switches functions to regulate DNA replication
Molecular & Computational biology
Hunting for TB's most vulnerable genes
Biotechnology
Reverse optogenetic tool developed
Molecular & Computational biology
Bacteria navigate on surfaces using a 'sense of touch'
Biotechnology
RNA breakthrough creates crops that can grow 50% more potatoes, rice
Molecular & Computational biology
Researchers develop tool to drastically speed up the study of enzymes
Evolution
Eyes wide shut: How newborn mammals dream the world they're entering
Biotechnology
Untwisting DNA reveals new force that shapes genomes
Biotechnology
DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins
Cell & Microbiology
Studying chromosomal rearrangements in yeast reveals potential avenue for cancer therapy
Biotechnology
Scientists harness the naturally abundant CRISPR-Cas system to edit superbugs
Biotechnology
How promiscuous protein droplets regulate immune genes
Ecology
Study mapping lobster genome could hold keys to strengthening species
Biotechnology
Nuclear factor Y subunit facilitates histone acetylation for salt tolerance in soybean
Cell & Microbiology
Giant extrachromosomal elements found in methane-metabolizing archaea
Biotechnology
Genome editing meets marsupials as lab cracks barriers to opossum eggs

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Astronomy
Image: Hubble spots squabbling galactic siblings
Paleontology & Fossils
Bird brains left other dinosaurs behind
Space Exploration
World's first commercial re-programmable satellite blasts into space
Space Exploration
Apollo 11 ascent stage may still be orbiting the moon
Space Exploration
US watchdog upholds SpaceX's Moon lander contract
Plants & Animals
Blood-sucking flies may be following chemicals produced by skin bacteria to locate bats to feed on
Ecology
In the absence of genetic variation, asexual invasive species find new methods of adapting to their environment
Polymers
'Greening' biomaterials and scaffolds used in regenerative medicine
Archaeology
Remains of ancient dogs found among early human ancestral remains in Georgia
Cell & Microbiology
A single cell type map of human tissues
Astronomy
The magnetic field in the galactic outflow of M82
Materials Science
Chemists discover a key to greener food production
Plasma Physics
Ultrafast X-ray provides new look at plasma discharge breakdown in water
Plants & Animals
Some birds observed stealing hair from living mammals
Astronomy
Astronomers discover how to feed a black hole
Optics & Photonics
Natural mineral hackmanite enables new method of x-ray imaging
Plants & Animals
Scientists create embryos to save northern white rhino
Cell & Microbiology
Chromosome positioning during sperm differentiation described
Nanophysics
Vanderbilt engineer the first to introduce low-power dynamic manipulation of single nanoscale quantum objects
Plants & Animals
Older males come out on top in battle of the breeding mosquitofish