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Molecular & Computational biology news

Research team models moving 'washers' that help DNA replicate
Knowing the structure of a complex biological system isn't nearly enough to understand how it works. It helps to know how the system moves.
Biotechnology
31 minutes ago
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A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling
A new research paper was published in Oncotarget on August 3, 2022, entitled, "A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling."
Cell & Microbiology
2 hours ago
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Discovery of non-conventional peptides in Vitis vinifera L. through peptidogenomics
Although some researchers have identified peptides through multiple methods, as in Arabidopsis and maize, the biological functions of most non-conventional peptides (NCPs) remain to be demonstrated. NCPs function by modulating ...
Molecular & Computational biology
2 hours ago
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A mutated eye offers a glimpse of a key protein for preventing cancer
About 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in significantly smaller eyes than those of wild zebrafish. Now, one of these researchers—Prof. ...
Cell & Microbiology
4 hours ago
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Mathematical method enables extraction of clear signals from single-cell RNA sequencing data
Since scientists first mapped the complete human genome, attention has now turned to the question of how cells use this master copy of genetic instructions. It is known that when genes are switched on, parts of the DNA sequences ...
Biotechnology
4 hours ago
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Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability
CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...
Biotechnology
5 hours ago
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72

Uncovering the secret of insulin growth factor ternary complex
Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses and children, but also body maintenance and metabolism in adults. IGF regulates cell proliferation, differentiation, and survival by ...
Cell & Microbiology
5 hours ago
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Molecules that promote plant-to-plant communications below ground
Plants have evolved elaborate mechanisms for detecting neighboring plants, which typically involve the perception of "cues'" inadvertently produced by their neighbors. Strigolactones are hormonal signaling molecules that ...
Molecular & Computational biology
7 hours ago
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Role of morphogens in tissue patterning in heart development
Morphogens are molecules that travel from cell to cell in order to pattern tissues in the embryo. These molecules are important not only for the embryo during development, but also for the adult during tissue repair. However, ...
Cell & Microbiology
7 hours ago
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Study could lead to new treatments for swallowing disorders
The average human swallows 500 to 700 times a day. Imagine if each of those swallows were a struggle.
Cell & Microbiology
23 hours ago
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Apple trees' natural response to virus mirrors genetic modification mechanism, study shows
Apple trees respond to a common viral infection by targeting a gene in the same pathway that genetic scientists are aiming at, find scientists from The University of Manchester. The discovery published in Current Biology ...
Plants & Animals
Aug 08, 2022
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Artificial intelligence tools predict DNA's regulatory role and 3D structure
Newly developed artificial intelligence (AI) programs have accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies ...
Biotechnology
Aug 08, 2022
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The novel leucine-rich repeat receptor-like kinase MRK1 regulates resistance to multiple stresses in tomato
Tomato (Solanum lycopersicum L.) is an economically important vegetable crop worldwide, and its production is threatened by temperature fluctuations and pathogen attacks, causing severe crop losses. In recent work published ...
Molecular & Computational biology
Aug 08, 2022
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How calcium ions get into the cellular power stations of plants
Calcium is a very special nutrient. In the cells of most living beings calcium ions function as so-called second messengers to transmit important signals. The same applies equally to animal, plant and fungal cells. Through ...
Cell & Microbiology
Aug 08, 2022
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Study links malignant hyperthermia to heat-hypersensitive mutant calcium channel proteins
Hot summer temperatures may have you reaching for a fan and an iced drink in your quest to keep cool. But now, researchers from Japan have found that some mutant proteins are even less tolerant of the heat, getting trapped ...
Cell & Microbiology
Aug 08, 2022
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Study reveals how lncRNAs modulate balance between plant immunity and growth
Researchers led by Prof. Zhang Xiaoming and Prof. Chen Jinfeng from the Institute of Zoology (IOZ) of the Chinese Academy of Sciences (CAS) and Prof. Qian Weiqiang from Peking University have unraveled a long non-coding RNA ...
Plants & Animals
Aug 08, 2022
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Regulation of fleshy fruit ripening: From transcription factors to epigenetic modifications
Recently, Professor Chunxiang You from Shandong Agricultural University and her colleagues published a review article titled "Regulation of fleshy fruit ripening: from transcription factors to epigenetic modifications" in ...
Molecular & Computational biology
Aug 08, 2022
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New-to-nature yeast chromosome could be game changer for industry
A completely new-to-nature yeast chromosome has been developed, paving the way for engineered yeast to be applied to an array of industrial applications.
Biotechnology
Aug 08, 2022
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Enhancers cooperate to regulate master transcription factors for sound receptor hair cell development
A study published in PNAS on Aug. 5 reveals the genome-wide chromatin accessibility of neonatal cochlear hair cells (HCs) and has identified two previously unknown Atoh1 enhancers. This study demonstrates that three Atoh1 ...
Cell & Microbiology
Aug 08, 2022
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Research team first to develop 3D structure of twinkle protein
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 05, 2022
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More news

Common weed may be 'super plant' that holds key to drought-resistant crops

Researchers show that locusts can 'sniff' out human cancer

Dual-plasmid editing system improves DNA digital storage potential

'Simple yet powerful': Seeing cell secretion like never before

Scientists characterize the potato L-type lectin StLecRK-IV.1, which negatively regulates late blight resistance

Exploring arcobacter risk to the food industry and human health

A year in the life of the mouse lemur

Team discovers new plant gene reprogramming mechanism

Drosophila embryonic development at single-cell resolution

A matter of concentration: Molecular mechanisms of water homeostasis

Bacterial membrane transporter helps pathogens to hide from immune system

Sterile mice produce rat sperm

How do PA, ABA, and CBF pathways synergistically regulate melon cold tolerance?
Other news

Understanding how motor proteins shape our cells

New analysis shows how sulfur clouds can form in Venus' atmosphere

CT scanner captures entire wooly mammoth tusk

New model sheds light on day/night cycle in the global ocean

Bats communicate and work together for more efficient foraging

Chemists achieve 'molecular editing' feat

Robot helps reveal how ants pass on knowledge

Individual genetics help determine composition of the gut microbiome

Digital dermatitis: Genes influence risk for global cattle disease

How do plants regulate their sugar metabolism?

Microbes emit nitrogen oxides—perhaps more than you think

Endogenous ceramide phosphoethanolamine modulates circadian rhythm and longevity in Drosophila

Giant viruses build a cell nucleus surprisingly like our own

'Youngest' antibiotic kills bacteria via a new two-step mechanism

RNA diversity in human tissues mapped with emerging sequencing technology

How the genome is packed into chromosomes that can be faithfully moved during cell division

Researchers crack 30-year-old mystery of odor switching in worms

Perovskite: New LED technology surpasses the lifetime milestone
