NAD, or nicotinamide adenine dinucleotide, probably needs no introduction. Together with its primary alter-egos NADH, NADP and NADPH, our private suite of pyridine-based nucleotides serve as hydride donors in some 400 enzymatic ...
In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.
Biotechnology
18 hours ago
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189
In the last five decades, we've learned a lot about the secret lives of proteins—how they work, what they interact with, the machinery that makes them function—and the pace of discovery is accelerating.
Biotechnology
18 hours ago
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86
A group of researchers developed a promising fix to CRISPR-Cas9's problem with unwanted genetic changes using a method that allows them to turn off gene-editing until it reaches key cell cycle phases where more accurate repairs ...
Biotechnology
23 hours ago
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121
A collaborative study on a plant intracellular immune receptor from researchers at the Max Planck Institute for Plant Breeding Research (MPIPZ) not only shows how an important resistance protein is activated during pathogen ...
Plants & Animals
Dec 04, 2020
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40
Researchers at the Garvan Institute of Medical Research have uncovered a new form of DNA modification in the genome of zebrafish, a vertebrate animal that shares an evolutionary ancestor with humans ~400 million years ago.
Biotechnology
Dec 04, 2020
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69
Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say.
Biotechnology
Dec 04, 2020
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14
A team of Johns Hopkins University researchers has developed a new software that could revolutionize how DNA is sequenced, making it far faster and less expensive to map anything from yeast genomes to cancer genes.
Biotechnology
Dec 03, 2020
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470
A team led by UT Southwestern has derived a new "intermediate" embryonic stem cell type from multiple species that can contribute to chimeras and create precursors to sperm and eggs in a culture dish.
Cell & Microbiology
Dec 03, 2020
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108
Over a quarter of all proteins in a cell are found in the membrane, where they perform vital functions. To fulfill these roles, membrane proteins must be reliably transported from their site of production in the cell to their ...
Cell & Microbiology
Dec 03, 2020
0
80
