Scientists upturn understanding of how key hormones act in cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related ...

Testis-specific gene involved in sex ratio regulation discovered

Although enormous progress has been made over the past few decades in genetics, molecular biology and biochemistry, the ways in which living beings orchestrate their internal processes at the microscopic scale is still full ...

Researchers find fat burning molecule in mice

Linked to serious health problems including cancer, diabetes and cardiovascular disease, obesity affects more than a third of adults in the United States. Presently, there are few safe and effective nonsurgical therapeutic ...

Cholera strain becomes unexpectedly resistant to infection by phages

Graduate student Kristen LeGault and assistant professor Kimberley Seed, both in the Department of Plant and Microbial Biology, specialize in the evolution of human pathogens and the viruses that infect bacteria, known as ...

Mapping of genetic control elements in the cerebellum

The mammalian cerebellum has long been associated almost exclusively with motor control, yet recent studies indicate that it also contributes to many higher brain functions. An international research team led by Prof. Dr. ...

Differentiating strong antibiotic producers from weaker ones

An untapped trove of desirable drug-like molecules is hidden in the genomes of Streptomyces bacteria—the same bacteria responsible for the first bacterial antibiotics to treat tuberculosis back in the 1940s.

Small proteins discovered to be regulators of the aging process

Scientists have discovered that the protein ubiquitin plays an important role in the regulation of the aging process. Ubiquitin was previously known to control processes such as signal transduction and metabolism. Prof. Dr. ...

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