Hunting for TB's most vulnerable genes

Developing drugs to combat tuberculosis, or TB, can be frustrating business. A gene essential to the bacteria's lifecycle is discovered, scientists rush to develop drugs that inhibit the target, and then—disappointment. ...

Bacteria navigate on surfaces using a 'sense of touch'

Many disease-causing bacteria such as Pseudomonas aeruginosa crawl on surfaces through a walk-like motility known as "twitching." Nanometers-wide filaments called type IV pili are known to power twitching, but scientists ...

Reverse optogenetic tool developed

A new optogenetic tool, a protein that can be controlled by light, has been characterized by researchers at Ruhr-Universität Bochum (RUB). They used an opsin—a protein that occurs in the brain and eyes—from zebrafish ...

Untwisting DNA reveals new force that shapes genomes

Advances in microscopy have enabled researchers to picture loops of DNA strands for the first time. The images reveal how the human genome organizes itself in three-dimensional space at much higher resolution than previously ...

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