How epithelial cells ward off viruses

A team led by LMU's Veit Hornung has shown that a protein found in skin cells recognizes a specific nucleic acid intermediate that is formed during virus replication. This recognition process subsequently induces a potent ...

Sestrin makes fruit flies live longer

Reduced food intake, known as dietary restriction, leads to a longer lifespan in many animals and can improve health in humans. However, the molecular mechanisms underlying the positive effects of dietary restriction are ...

CRISPRi screens reveal sources of metabolic robustness in E.coli

Metabolic robustness, the ability of a metabolic system to buffer changes in its environment, is not always a welcome feature for microbiologists: it interferes with metabolic engineering or prevents that antibiotics kill ...

Researchers identify genetics behind deadly oat blight

A multi-institution team co-led by a Cornell University researcher has identified the genetic mechanisms that enable the production of a deadly toxin called Victorin—the causal agent for Victoria blight of oats, a disease ...

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