AI-designed miniproteins switch key cell receptors on and off

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a living cell. They communicate with nearly every physiological process in our bodies—from the ability ...

Second ribosome binding site helps explain how tetracyclines work

For decades, doctors have widely used tetracyclines for conditions ranging from acne to tick-borne illnesses. Using high-resolution imaging technology, researchers in the laboratory of Christopher Bunick, MD, Ph.D., associate ...

Faster gene screening method targets deadly fungus

Researchers at the University of Guelph have developed a faster way to identify potential drug targets against a dangerous fungal pathogen, allowing for the study of hundreds or thousands of genes simultaneously instead of ...

Copper-based sensor explains key defense signaling in stressed plants

Researchers at the Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, together with collaborators from RIKEN Center for Sustainable Resource Science (RIKEN CSRS) and The University of Osaka, have uncovered ...

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