Structural insights into tiny bacterial harpoons

New research sheds light onto how different bacterial species can build complex nano-harpoons with different protein building blocks. Bacteria use these harpoons called Type VI secretion systems to inject toxins into nearby ...

New therapeutic approach to combat African sleeping sickness

Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research undertaken under the supervision of Professor Ute Hellmich of Johannes Gutenberg ...

Mega docking library poised to speed drug discovery

Researchers have launched an ultra-large virtual docking library expected to grow to more than 1 billion molecules by next year. It will expand by 1000-fold the number of such "make-on-demand" compounds readily available ...

Molecular Velcro helps illuminate DNA repair

Using a piece of molecular "Velcro" to attach a light-emitting probe to a protein molecule, University of Wollongong (UOW) researchers have unlocked the mystery of how an important protein goes about repairing damaged DNA ...

Biology of our ancient ancestor takes shape

The recent discovery of a new lineage of microbes has overturned biologists' understanding of the evolution of complex life on Earth. Genomic studies of Asgard archaea revealed that they carry many genes previously thought ...

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