Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

Mitochondria efficiently adapt to changing metabolic conditions

A recent study explains an essential component for proper mitochondrial function: The protein complexes MICOS and ATP synthase can communicate with each other. Dr. Heike Rampelt and Prof. Dr. Nikolaus Pfanner at the Institute ...

How some tissues can 'breathe' without oxygen

Humans need oxygen molecules for a process called cellular respiration, which takes place in our cells' mitochondria. Through a series of reactions called the electron transport chain, electrons are passed along in a sort ...

New animations breathe life into complex scientific concepts

The fundamental process of cellular respiration—how cells make energy—has been brought to life in a new series of biomedical animations created by wehi.tv, in partnership with HHMI Biointeractive, an initiative of the ...

Researchers reveal molecular structures involved in plant respiration

All plants and animals respire, releasing energy from food. At the cellular level, this process occurs in the mitochondria. But there are differences at the molecular level between how plants and animals extract energy from ...

Structure of a mitochondrial ATP synthase

ATP synthase is a universal molecular machine for energy conversion. By coupling to cellular respiration in mitochondria, it catalyzes conversion of chemical energy of cells.

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