Cyclic peptides often exhibit low membrane permeability that can be significantly improved via amide-to-ester substitutions, as demonstrated by researchers from Tokyo Institute of Technology (Tokyo Tech). The utilization ...
Biochemistry
Mar 17, 2023
0
65
A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.
Biochemistry
Nov 14, 2022
0
283
This story begins several billion years ago. There's only chemistry, no biology—that is, plenty of chemical compounds exist on Earth, but life hasn't yet emerged. Then, among myriads of randomly self-assembled chemical ...
Evolution
Sep 14, 2022
1
832
Protein function and activity are determined by both their assembly and secondary structure. Abnormalities related to either protein aggregation or secondary structure can lead to neurodegenerative diseases. In a new study, ...
Bio & Medicine
Jul 14, 2022
0
10
The formation of peptide bonds—the chemical bond between amino acids—in protein synthesis is one of the most important biochemical reaction steps. Without the development of structurally and catalytically active polymers, ...
Materials Science
Dec 13, 2021
0
8
Biological energy flows, such as in photosynthesis and respiration, depend on the transfer of electrons from one molecule to another. Despite its importance to sustaining life, factors governing the rate of electron transfer, ...
Biochemistry
Apr 14, 2021
0
96
NUS researchers have identified post-translational modifying enzymes in bacteria that can create a new family of cyclic peptides for new therapeutics.
Biochemistry
Oct 15, 2020
0
40
For the first time, researchers have detected protease activity with surface-enhanced Raman spectroscopy (SERS) performed using a tiny waveguide. The work paves the way to real-time, label-free lab-on-a-chip protease monitoring, ...
Optics & Photonics
Sep 8, 2020
0
7
Uncovering how the first biological molecules (like proteins and DNA) arose is a major goal for researchers attempting to solve the origin of life. Today, chemists at Saint Louis University, in collaboration with scientists ...
Biochemistry
Oct 4, 2019
8
192
One of the tricks you learn hunting dinosaurs in Canada is to look for orange. Dinosaur bones are dull browns, tans, and greys. But in the middle of the drab sandstones of the badlands—a dry landscape where wind and water ...
Archaeology
Jul 26, 2019
2
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