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Mystery solved: Tiny protein-activator responsible for brain cell damage in Huntington disease

Johns Hopkins brain scientists have figured out why a faulty protein accumulates in cells everywhere in the bodies of people with Huntington's disease (HD), but only kills cells in the part of the brain that controls movement, ...

Medicine & Health / Medical research

created Jun 04, 2009 | popularity 5 / 5 (10) | comments 0

Huntington's disease breakthrough equals hope for patients

A huge leap forward in understanding Huntington's disease may give patients hope for a cure.

Medicine & Health / Medical research

created Feb 22, 2011 | popularity 5 / 5 (8) | comments 2 | with audio podcast

Old gastrointestinal drug slows aging

Recent animal studies have shown that clioquinol - an 80-year old drug once used to treat diarrhea and other gastrointestinal disorders - can reverse the progression of Alzheimer's, Parkinson's and Huntington's diseases. ...

Chemistry /

created Jan 06, 2009 | popularity 4.7 / 5 (7) | comments 0

Huntington's disease deciphered

Researchers at the University of Illinois at Chicago College of Medicine have discovered how the mutated huntingtin gene acts on the nervous system to create the devastation of Huntington's disease. The report of their findings ...

Medicine & Health / Neuroscience

created Jun 14, 2009 | popularity 5 / 5 (6) | comments 0

Faulty clean-up process may be key event in Huntington's disease (w/ Video)

In a step towards a possible treatment for Huntington's disease, scientists at Albert Einstein College of Medicine of Yeshiva University have shown for the first time that the accumulation of a mutated protein may explain ...

Medicine & Health / Neuroscience

created Apr 11, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Nano-motors facilitate communication between brain cells

(PhysOrg.com) -- MRC-funded scientists led by Dr Josef Kittler (University College London Neuroscience) have identified how nano-sized motors in nerve cells help to regulate the balance of communication in ...

Medicine & Health / Neuroscience

created Jan 22, 2010 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Novel method results in promising drugs for Huntington's disease therapeutics

Huntington's disease (HD) is an incurable progressive neurodegenerative genetic disorder which affects motor coordination and leads to cognitive decline and dementia.

Medicine & Health / Medical research

created Jan 26, 2011 | popularity 4.7 / 5 (3) | comments 0

Researchers show efficacy of gene therapy in mouse models of Huntington's disease

Researchers at the California Institute of Technology (Caltech) have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's ...

Medicine & Health / Neuroscience

created Oct 30, 2009 | popularity 5 / 5 (2) | comments 0

New hope in fight against Huntington's disease

Hope for new ways of treating devastating neurodegenerative disorders such as Huntington's disease has been raised by a trans-Atlantic team of researchers thanks to the use of cutting-edge genetic techniques.

Chemistry / Biochemistry

created Jan 10, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Research offers clue to halt Huntington's disease

(PhysOrg.com) -- Surprising findings from a study into the brains of transgenic mice carrying the Huntington's disease mutation could pave the way for treatments which delay the onset and progression of this devastating genetic ...

Medicine & Health / Medical research

created Mar 25, 2011 | popularity 3.5 / 5 (2) | comments 0 | with audio podcast

Huntington disease begins to take hold early on

A global analysis of brain proteins over a 10-week period in a mouse model of Huntington Disease has revealed some new insights into this complex neurodegenerative disorder. For example, profound changes (comparable to those ...

Medicine & Health / Diseases, Conditions, Syndromes

created Apr 16, 2009 | popularity 5 / 5 (1) | comments 0

New hope for treatment of neurodegenerative disorder

Researchers from the University of Southern California have taken an important first step toward protecting against Huntington disease using gene therapy.

Chemistry / Biochemistry

created Apr 20, 2009 | popularity 5 / 5 (1) | comments 0

Researchers gain insight into mechanism underlying Huntington's

Researchers at the University of Kentucky Markey Cancer Center and Graduate Center for Toxicology (GCT) have gained new insight into the genetic mechanisms underlying Huntington's disease and other neurodegenerative or neuromuscular ...

Biology / Cell & Microbiology

created Jul 13, 2009 | popularity 5 / 5 (1) | comments 0

Scientists make important step toward stopping plaque-like formations in Huntington's disease

They might not be known for their big brains, but fruit flies are helping to make scientists and doctors smarter about what causes Huntington's disease and how to treat it. New research, published in the journal Genetics descri ...

Medicine & Health / Medical research

created May 21, 2010 | popularity 5 / 5 (1) | comments 0

Huntington's disease discovery provides new hope for treatment

Australian scientists have identified the behaviour of the mutant protein 'huntingtin' which leads to the fatal Huntington's disease providing potential targets to treat the disease, a University of Melbourne study reveals.

Chemistry / Biochemistry

created Jul 28, 2010 | popularity 5 / 5 (1) | comments 0