An immunosuppressant is any substance that performs immunosuppression of the immune system. They may be either exogenous, as immunosuppressive drugs, or endogenous, as ,e. g., testosterone. When the immune system function is suppressed, there is an increased susceptibility to infectious diseases and cancers.
The term immunotoxin is also sometimes used (incorrectly) to label undesirable immunosuppressants, such as various pollutants. Polychlorinated biphenyls (PCB) and the herbicide DDT are immunosuppressants.[citation needed]
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