Search results for CRISPR

Cell & Microbiology Mar 29, 2024

Gene editing technology reveals molecular mechanisms governing diatom population density signals

The intricate dynamics of diatom blooms, influenced by a myriad of external factors and internal signals, continue to fascinate scientists. After recognizing the potential role of density perception and intracellular signaling ...

Cell & Microbiology Mar 29, 2024

Scientists discover a key quality-control mechanism in DNA replication

When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and is fraught with risks of mutation, which ...

Cell & Microbiology Mar 29, 2024

Constructing 'on-gel' alveolar organoids as a new screening platform

A study led by Professor Shimpei Gotoh (Department of Clinical Application), introduces a new culturing method to generate alveolar organoids suitable for medium- and high-throughput screening and identified several chemicals ...

Cell & Microbiology Mar 29, 2024

Novel role for metabolites in cellular metabolism discovered

Investigators led by Issam Ben-Sahra, Ph.D., associate professor of Biochemistry and Molecular Genetics, have discovered how cellular metabolism fluctuates in response to changes in levels of pyrimidines, metabolites used ...

Cell & Microbiology Mar 28, 2024

Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment

Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. ...

Biotechnology Mar 26, 2024

New genetic analysis tool tracks risks tied to CRISPR edits

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields. Now scientists are applying the technology's immense potential to human health and disease, ...

Evolution Mar 22, 2024

Decoding the shared genetic toolkit for male sex determination

Researchers from the Max Planck Institute for Biology Tübingen have broken new ground by demonstrating that an HMG-box gene in brown algae is crucial for determining male sex. This breakthrough significantly expands our ...

Biotechnology Mar 22, 2024

Messenger RNAs with multiple 'tails' could lead to more effective therapeutics, say researchers

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines. But mRNAs, which are genetic sequences that instruct the body to produce proteins, ...

Plants & Animals Mar 21, 2024

'Courtship' gene shows different effects in two fruit fly species

A gene associated with courtship behavior in fruit flies does not operate the same way in two different fruit fly species, a new study finds. The work demonstrates that conserved genes—the same genes found across species—do ...

Bio & Medicine Mar 20, 2024

Advances and applications of nanoparticles in cancer therapy

The research team of Prof. Changyang Gong from the Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University has published a new review showing that rapid growth ...

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