Research news on virology

Virology is the branch of biological sciences that investigates viruses and virus-like agents, encompassing their molecular structure, genome organization, replication strategies, evolution, and interactions with host cells and organisms. It integrates methods from molecular biology, genetics, biochemistry, immunology, and cell biology to elucidate viral entry, gene expression, assembly, egress, and mechanisms of pathogenesis. Virology also addresses virus classification, epidemiology, host range, and antiviral resistance, and underpins the rational design of vaccines, antiviral drugs, viral vectors for gene delivery, and oncolytic virotherapies, as well as biosurveillance and containment strategies for emerging and re-emerging viral diseases.

Lemurs fall prey to human herpes virus

The last time you had a cold sore, you might have fretted about how long it would hang around. Perhaps you avoided reflective surfaces. It's unlikely you worried about dying from it.

Human norovirus capsid shifts between two shapes, cryo-EM reveals

A research team led by Kazuyoshi Murata has discovered that virus-like particles (VLPs) of human norovirus genotype GII.3 are not structurally rigid, but can adopt two distinct conformational states, similar to those previously ...

Uncovering the structure of the poxvirus 'portal complex'

Poxviruses have a long history in human disease as well as medicine: The first-ever vaccine was developed to protect against smallpox, which has since been eradicated. Despite this, scientists still don't fully understand ...

Why the hepatitis E virus cannot infect mice

Many viruses can infect both humans and animals, including hepatitis E virus. This virus is often transmitted to humans via contaminated meat products, such as by ingesting raw or undercooked pork or wild game. However, mouse ...

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