Research news on tremor

Tremor is a rhythmic, involuntary, oscillatory movement of a body part resulting from alternating or synchronous contractions of reciprocally innervated muscles, typically around a joint. Phenomenologically, tremors are characterized by their frequency, amplitude, distribution, and activation condition (rest, postural, kinetic, or intention). They arise from pathological or physiological alterations in central motor networks, particularly involving cerebello-thalamo-cortical and basal ganglia circuits, and can be modulated by peripheral feedback. Tremor is a core motor phenomenon in various neurological disorders, where its spatiotemporal features are crucial for differential characterization, quantification, and pathophysiological investigation.