Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
Most drugs work by inhibition: they block a protein's activity but leave the protein itself intact. Targeted protein degradation takes a fundamentally different approach, harnessing the cell's own quality-control machinery ...
Biotechnology
May 12, 2026
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5
Sleep is a vital physiological process that allows humans and other animals to restore both the mind and body, while also consolidating memories, clearing out toxins and regulating their metabolism. Several past studies showed ...
In flowering plants, the transition from cross-fertilization (outcrossing) to self-fertilization has evolved repeatedly across species. This shift is often accompanied by a well-known set of traits collectively called the ...
Plants & Animals
May 12, 2026
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6
Stem cells are the original cell type from which all other cells and tissues in the body develop through a very tightly regulated process. However, how stem cells differentiate in addition to gene-control systems, such as ...
Cell & Microbiology
May 12, 2026
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10
Until now, studying the genetic processes in cells required destroying them—making it impossible to observe these processes over extended periods of time. A team from the Technical University of Munich (TUM) and Helmholtz ...
Cell & Microbiology
May 10, 2026
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42
Dysfunction resulting from mitochondrial DNA mutations has been implicated in multiple human pathologies, including neurodegenerative disorders, metabolic syndromes, cancer and cardiovascular disease. The stress from mtDNA ...
Cell & Microbiology
May 7, 2026
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Scientists have uncovered more than 1,700 new proteins that could have implications for human diseases, including cancer. Mostly very small, these proteins were found in what's called the "dark proteome," which covers gene ...
Biotechnology
May 6, 2026
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200
For the first time, scientists at University of Leeds reveal a complex mechanism behind blood clotting. The findings, published in Science Advances, visualize a key component of blood clotting—platelet myosin—and how it is ...
Cell & Microbiology
May 5, 2026
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14
Scientists at Keele University have created the first detailed map of the genetic "switches" that control reproduction in disease-carrying insects such as Anopheles gambiae, the mosquito species most responsible for malaria ...
Biotechnology
May 5, 2026
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10
One of life's many mysteries is how it ended up choosing only a set of 20 amino acids to build proteins for its wide catalog of organisms, from single-celled bacteria to behemoth whales. From a chemical standpoint, many of ...
