Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
Cornell researchers have discovered a new way cells regulate how they respond to stress, identifying an interaction between two proteins that helps keep a critical cellular recycling system in balance. The findings show that ...
Cell & Microbiology
Feb 9, 2026
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13
The nuclear envelope (NE) is a dynamic and selective barrier that organizes genome function and nucleocytoplasmic communication, and its structural deterioration is a hallmark of aging associated with diverse human diseases. ...
Cell & Microbiology
Feb 9, 2026
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64
A Northwestern Medicine study has shed light on one of the most intricate construction projects in biology: how cells build and coordinate the internal scaffolding needed to create a healthy egg. The research, published in ...
Cell & Microbiology
Feb 7, 2026
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207
For decades, scientists assumed that order drives efficiency. Yet in the bustling machinery of mitochondria—the organelles that crank out adenosine triphosphate (ATP), the universal "energy currency" of cells—one of the most ...
Cell & Microbiology
Feb 6, 2026
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129
Scientists have identified the molecular interactions that give spider silk its exceptional strength and flexibility, opening the door to new bio-inspired materials for aircraft, protective clothing and medical applications, ...
Plants & Animals
Feb 6, 2026
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30
Watching proteins move as they drive the chemical reactions that sustain life is one of the grand challenges of modern biology. In recent years, X-ray free-electron lasers, or XFELs, have begun to meet that challenge, capturing ...
Biotechnology
Feb 5, 2026
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25
Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint—the genetic information. Here, the basic building blocks of proteins, amino acids, are assembled ...
Cell & Microbiology
Feb 5, 2026
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97
Muscles make up nearly 40% of the human body and power every move we make, from a child's first steps to recovery after injury. For some, however, muscle development goes awry, leading to weakness, delayed motor milestones ...
Molecular & Computational biology
Feb 5, 2026
0
83
In biology, many RNA molecules act as sophisticated microscopic machines. Among them, riboswitches function as tiny biological sensors, changing their 3D shape upon binding to a specific metabolite. This shape-change acts ...
Biotechnology
Feb 5, 2026
0
17
Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The inability to consistently, ...
Molecular & Computational biology
Feb 5, 2026
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