Researchers reveal new cellular mechanical transducer
A research team has uncovered a novel regulator governing how cells respond to mechanical cues. Their findings appear in Nature Cell Biology.
A research team has uncovered a novel regulator governing how cells respond to mechanical cues. Their findings appear in Nature Cell Biology.
Cell & Microbiology
May 10, 2024
0
3
Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.
Cell & Microbiology
Apr 22, 2024
0
42
EPFL researchers have developed GEMLI, a pioneering tool that could democratize and vastly improve how we study the journey of cells from their embryonic state through to specialized roles in the body, as well as their changes ...
Cell & Microbiology
Apr 11, 2024
0
2
Some stem cells have a natural ability to divide into more cells and develop into various specialized blood, bone or muscle cells. These pluripotent stem cells offer great promise for new cell treatments and regenerative ...
Cell & Microbiology
Apr 4, 2024
0
6
A team of researchers led by Professor Koji Eto (Department of Clinical Application) recently discovered the importance of a microRNA-based regulatory mechanism for enhancing the quality and quantity of platelets generated ...
Cell & Microbiology
Mar 29, 2024
0
47
Embryonic development, also known as embryogenesis, is a cornerstone in understanding the origins of life. But studying this marvel of intricate and layered biological processes in people faces considerable challenges. Early-stage ...
Biotechnology
Feb 7, 2024
0
17
How do organisms form limbs in the womb? Scientists have been striving to answer this question not only to deepen our understanding of evolution and embryonic development, but also to help make the dream of regenerating partial ...
Cell & Microbiology
Feb 5, 2024
0
91
The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be condensed to fit inside the nucleus. DNA condensation is not ...
Cell & Microbiology
Jan 17, 2024
0
65
A research team led by Junior Associate Professor Masato Nakagawa (Department of Life Science Frontiers) investigated the effects of basic fibroblast growth factor (bFGF) and its interactions with fibroblast growth factor ...
Cell & Microbiology
Jan 17, 2024
0
1
Sequencing all of the RNA in a cell can reveal a great deal of information about that cell's function and what it is doing at a given point in time. However, the sequencing process destroys the cell, making it difficult to ...
Biotechnology
Jan 10, 2024
0
9
Embryonic stem cells (ES cells) are stem cells derived from the inner cell mass of an early stage embryo known as a blastocyst. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells.
Embryonic Stem (ES) cells are pluripotent. This means they are able to differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. These include each of the more than 220 cell types in the adult body. Pluripotency distinguishes ES cells from multipotent progenitor cells found in the adult; these only form a limited number of cell types. When given no stimuli for differentiation, (i.e. when grown in vitro), ES cells maintain pluripotency through multiple cell divisions. The presence of pluripotent adult stem cells remains a subject of scientific debate; however, research has demonstrated that pluripotent stem cells can be directly generated from adult fibroblast cultures.
Because of their plasticity and potentially unlimited capacity for self-renewal, ES cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. However Diseases treated by these non-embryonic stem cells include a number of blood and immune-system related genetic diseases, cancers, and disorders; juvenile diabetes; Parkinson's; blindness and spinal cord injuries. Besides the ethical concerns of stem cell therapy (see stem cell controversy), there is a technical problem of graft-versus-host disease associated with allogeneic stem cell transplantation. However, these problems associated with histocompatibility may be solved using autologous donor adult stem cells or via therapeutic cloning.
This text uses material from Wikipedia, licensed under CC BY-SA