Bioreactor keeps cell culture conditions under control

A cell-culturing technique developed by KAUST scientists helps to create biological conditions that more closely mirror physiological environments compared to standard protocols used in most laboratories today.

Migration as morality politics

Migration often serves as an arena for conflicting values. In this context, religious groups, civil society organizations and local authorities often show a more liberal attitude than the state. The political scientist Julia ...

Making lab-grown brain organoids 'brainier'

By using stem cells to grow miniature brain-like organs in the lab, scientists have opened a new avenue for studies of neurological development, disease and therapies that can't be conducted in living people. But not all ...

What can sea squirts tell us about neurodegeneration?

A tiny marine creature with a strange lifestyle may provide valuable insights into human neurodegenerative disorders, such as Alzheimer's disease, according to scientists at Stanford Medicine.

How did vertebrates first evolve jaws?

Five-hundred million years ago, it was relatively safe to go back in the water. That's because creatures of the deep had not yet evolved jaws. In a new pair of studies in eLife and Development, scientists reveal clues about ...

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Stem cell

Stem cells are cells found in most, if not all, multi-cellular organisms. They are characterized by the ability to renew themselves through mitotic cell division and differentiating into a diverse range of specialized cell types. Research in the stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s. The two broad types of mammalian stem cells are: embryonic stem cells that are isolated from the inner cell mass of blastocysts, and adult stem cells that are found in adult tissues. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin or intestinal tissues.

Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture. Highly plastic adult stem cells from a variety of sources, including umbilical cord blood and bone marrow, are routinely used in medical therapies. Embryonic cell lines and autologous embryonic stem cells generated through therapeutic cloning have also been proposed as promising candidates for future therapies.

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