News tagged with ribosomal protein

Detour leads to antibiotic resistance

Ludwig Maximilian University researchers have used cryo-electron microscopic imaging to characterize the structural alterations in the bacterial ribosome that are required for induction of resistance to the ...

Mar 28, 2014
3 / 5 (1) 0

Protein 'rescues' stuck cellular factories

Using a powerful data-crunching technique, Johns Hopkins researchers have sorted out how a protein keeps defective genetic material from gumming up the cellular works. The protein, Dom34, appears to "rescue" protein-making ...

Mar 19, 2014
5 / 5 (4) 0

Designer of protein factories exposed

For 10 years, Patrick Cramer and his colleagues at Ludwig-Maximilians-Universitaet (LMU) in Munich have probed the structure of RNA polymerase I, a crucial cog in the machinery of all cells. Now they unveil ...

Oct 24, 2013
5 / 5 (2) 0

Piloting ribosomes past proline pairs

Certain proteins are known to require Translation Factor EF-P for their synthesis, and a new study enlarges the size of the set. As some of its members are involved in bacterial pathogenicity, the results ...

Sep 10, 2013
3.3 / 5 (3) 0 | with audio podcast

How 'junk DNA' can control cell development

Researchers from the Gene and Stem Cell Therapy Program at Sydney's Centenary Institute have confirmed that, far from being "junk", the 97 per cent of human DNA that does not encode instructions for making proteins can play ...

Aug 02, 2013
4.9 / 5 (9) 1 | with audio podcast

A roundabout route to protein production

Proteins are typically encoded by linear strands of messenger RNA (mRNA). These mRNA molecules are translated into polypeptide chains by ribosomes, with each ribosomal read-through of the mRNA generating ...

Jul 12, 2013
5 / 5 (2) 0

The ribosome: A new target for antiprion medicines

New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery ...

Jul 02, 2013
5 / 5 (1) 0