Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic ...
Cell & Microbiology
Aug 8, 2023
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5
The mechanisms of RNA-binding proteins (RBPs)-mediated post-transcriptional regulation of pre-existing mRNAs, which is essential for spermatogenesis, remain poorly understood.
Cell & Microbiology
Jul 25, 2023
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1
All biological processes in our cells are constantly monitored to prevent the accumulation of defective proteins. In the worst case, such protein clumps can trigger diseases. The synthesis of new proteins is particularly ...
Cell & Microbiology
Jun 20, 2023
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248
Scientists at the University of Illinois Chicago have found that a peptide from fruit flies could lead to new antibiotics.
Cell & Microbiology
Jun 6, 2023
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38
In a discovery fundamental to the inner workings of cells, scientists have discovered that if oxidative stress damages protein factories called ribosomes, repair crews may move in to help fix the damage so work can quickly ...
Cell & Microbiology
Apr 21, 2023
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77
Antibiotic resistance (ARE) is a threat to human health worldwide, as diverse proteins allow pathogenic bacteria to develop increasing levels of resistance to antibiotic medicines. Now, a team from the University of Tsukuba ...
Cell & Microbiology
Mar 30, 2023
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4
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have discovered a mechanism involving ribosomes which helps the heart toggle between a 'regular maintenance mode' for day-to-day function and an 'energy-boost ...
Cell & Microbiology
Mar 7, 2023
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43
Ribosomes are the nanomachines of the cell whose task is the correct synthesis of proteins. Researchers at the Heidelberg University Biochemistry Center are studying the emergence of these "protein factories", also known ...
Cell & Microbiology
Feb 8, 2023
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58
Ribosomes, the tiny protein-producing factories within cells, are ubiquitous and look largely identical across the tree of life. Those that keep bacteria chugging along are, structurally, not much different from the ribosomes ...
Cell & Microbiology
Dec 8, 2022
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18
How do cells manage to quickly adapt their growth to changing environmental conditions? A new study by a research team from Würzburg provides an answer to this question.
Cell & Microbiology
Oct 14, 2022
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37
