Related topics: dna · genes · protein · gene expression · cells

SABER tech gives DNA and RNA visualization a boost

Researchers have been using "Fluorescence in situ hybridization" (FISH) analysis for decades to literally fish for specific DNA and RNA sequences in intact cells and tissues within their vast seas of nucleic acid molecules. ...

How potatoes could become sun worshippers

If there's one thing potato plants don't like, it's heat. If the temperature is too high, potato plants form significantly lower numbers of tubers, or sometimes none at all. Biochemists at Friedrich-Alexander-Universität ...

Symbionts as lifesavers

When people fall ill from bacterial infection, the first priority is to treat the disease. But where do these pathogens come from, and how do they thrive in the environment before the infection occurs? An international team ...

A way to minimize unexpected base edits to cellular RNA

A team of researchers with the Broad Institute of Harvard and MIT has found evidence showing that using base editors can lead to unexpected RNA cellular edits. In their paper published in the journal Science Advances, the ...

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RNA

Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate. RNA is very similar to DNA, but differs in a few important structural details: in the cell, RNA is usually single-stranded, while DNA is usually double-stranded; RNA nucleotides contain ribose while DNA contains deoxyribose (a type of ribose that lacks one oxygen atom); and RNA has the base uracil rather than thymine that is present in DNA.

RNA is transcribed from DNA by enzymes called RNA polymerases and is generally further processed by other enzymes. RNA is central to the synthesis of proteins. Here, a type of RNA called messenger RNA carries information from DNA to structures called ribosomes. These ribosomes are made from proteins and ribosomal RNAs, which come together to form a molecular machine that can read messenger RNAs and translate the information they carry into proteins. There are many RNAs with other roles – in particular regulating which genes are expressed, but also as the genomes of most viruses.

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