RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer. These therapeutics ...
Molecular & Computational biology
Aug 20, 2024
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35
For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upward of seven days, making it a bottleneck in the parasite's ...
Cell & Microbiology
Aug 20, 2024
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14
In recent years, public health measures, surveillance, and vaccination have helped bring about significant progress in reducing the impact of seasonal flu epidemics, caused by human influenza viruses A and B. However, a possible ...
Molecular & Computational biology
Aug 19, 2024
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154
RNA hit prime time during the COVID-19 pandemic, when the average American waiting in line for their shot knew that the vaccines from Pfizer-BioNTech and Moderna were made using mRNA. But while RNA has since become a part ...
Molecular & Computational biology
Aug 14, 2024
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0
Researchers at the University of Bayreuth have established a new optogenetic approach that can control the bacterial production of proteins at the mRNA level using blue light. The new system gates the activation of the genetic ...
Biotechnology
Aug 14, 2024
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1
Cold Spring Harbor Laboratory (CSHL) has begun to unravel a mystery millennia in the making. Our story begins 9,000 years ago. It was then that maize was first domesticated in the Mexican lowlands. Some 5,000 years later, ...
Molecular & Computational biology
Aug 7, 2024
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25
Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development. ...
Molecular & Computational biology
Aug 7, 2024
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0
A team of zoologists at Goethe University Frankfurt, in Germany, working with a colleague from Universidad del Quindío, Armenia, in Colombia, has found evidence that some species of poison frogs produce pheromones in one ...
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, IMDEA Nanoscience (Madrid, Spain) and CNB-CSIC (Madrid, Spain) report in ACS Nano experiments that reveal a cycle of conformational stages that ...
Bio & Medicine
Aug 5, 2024
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35
A biochemical breakthrough using simple carbon atoms, by Ken Yamada, Ph.D., and Anastasia Khvorova, Ph.D., has dramatically improved the stability and efficacy of a potential oligonucleotide therapeutic platform in mice. ...
Biotechnology
Aug 5, 2024
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