Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now ...
Biochemistry
Jun 12, 2019
0
14
Groundbreaking research at the new long-wavelength macromolecular crystallography beamline (I23) at Diamond Light Source has for the first time demonstrated the location of potassium ions in bacterial ribosomes. Ribosomes ...
Biochemistry
Jun 7, 2019
0
163
Researchers from Marvin Tanenbaum's group at the Hubrecht Institute have shown that translation of the genetic information stored in our DNA is much more complex than previously thought. This discovery was made by developing ...
Cell & Microbiology
Jun 6, 2019
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876
Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the messages that decode ...
Molecular & Computational biology
May 24, 2019
1
420
A team of researchers at the RIKEN Center for Biosystems Dynamics Research in Japan has developed a tool to prevent neurogenerative diseases. They have demonstrated a way to observe the molecular mechanism that switches control ...
To perform the task for which they have been synthesized, proteins must first assemble to form effective cellular "machines." But how do they recognize their partners at the right time? Researchers at the University of Geneva ...
Cell & Microbiology
Jan 28, 2019
0
17
The genome sizes of viruses are usually relatively small. To increase information content of the genome, many viruses employ a translation recoding mechanism dubbed programmed ribosomal frameshifting.
Cell & Microbiology
Jan 28, 2019
0
2
Proteins do most of the real work in cells and are modified in accordance with functional requirements. An LMU team has now shown how proteins are chemically altered on the ribosome, even before they fold into the active ...
Cell & Microbiology
Dec 20, 2018
0
15
An international team including the University of Valencia has proven that the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to biochemical research for ...
Cell & Microbiology
Dec 20, 2018
0
3
The human genome contains regions that "code" for proteins, which means they have instructions to make protein molecules with specific functions in the body. But Yale researchers have discovered several protein-coding genes ...
Molecular & Computational biology
Dec 13, 2018
0
40
