Related topics: protein · gene expression · rna molecules · cells · genes

Factors that ensure cellular protein production

Defects in tRNA biogenesis influence gene expression and are associated with many types of human diseases, such as cancer and neurological diseases. In his thesis, Fu Xu contributes to new knowledge about the factors that ...

Virus multiplication in 3-D

For viruses to multiply, they usually need the support of the cells they infect. In many cases, only in their host's nucleus can they find the machines, enzymes and building blocks with which they can multiply their genetic ...

MicroRNA comprehensively analyzed

Messenger RNA transmits genetic information to the proteins, and microRNA plays a key role in the regulation of gene expression. Scientists from the Moscow Institute of Physics and Technology and the Research Centre for Medical ...

A matter of concentration

Plants can grow whole new organs with the help of pluripotent stem cells throughout their entire lives. When necessary, these stem cells can develop into any type of cell within an organism. The biologist Prof. Dr. Thomas ...

Molecular biologists reveal new insights into tumor progression

University of Delaware molecular biologist Mona Batish and collaborators at Harvard Medical School and University of California, Los Angeles, have identified a new circular ribonucleic acid (RNA) that increases tumor activity ...

Blue light for RNA control

Messenger RNA molecules contain genetic information and thus control the synthesis of proteins in living cells. Biochemists at the University of Bayreuth and the University of Bonn have now discovered a way to regulate this ...

Protein quality control and mitochondria

Protein aggregates are toxic for mitochondrial function, and thus disrupt the supply of chemical energy to their host cells. An LMU team has characterized a protein complex that prevents the build-up of such deposits in the ...

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Messenger RNA

Messenger ribonucleic acid (mRNA) is a molecule of RNA encoding a chemical "blueprint" for a protein product. mRNA is transcribed from a DNA template, and carries coding information to the sites of protein synthesis: the ribosomes. Here, the nucleic acid polymer is translated into a polymer of amino acids: a protein. In mRNA as in DNA, genetic information is encoded in the sequence of nucleotides arranged into codons consisting of three bases each. Each codon encodes for a specific amino acid, except the stop codons that terminate protein synthesis. This process requires two other types of RNA: transfer RNA (tRNA) mediates recognition of the codon and provides the corresponding amino acid, while ribosomal RNA (rRNA) is the central component of the ribosome's protein manufacturing machinery.

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