Circular ribonucleic acids (circRNAs) are a promising platform for gene expression studies as a stable and prevalent ribonucleic acid in eukaryotic cells, which arise from back-splicing. In a new report now published in Nature ...
Life runs on ribosomes. Every cell on Earth needs ribosomes to translate genetic information into all the proteins needed for the organism to function—and to in turn make more ribosomes. But scientists still lack a clear ...
Cell & Microbiology
Jul 6, 2023
0
402
Researchers from Southwest University in China have constructed the entire chromosomal-scale genome assembly and complete spidroin gene set of the golden orb-weaving spider, Trichonephila clavata, known for its especially ...
For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented ...
Molecular & Computational biology
Oct 3, 2022
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2302
RNA sequencing allows scientists to study the expression of genes in a cell. Since messenger RNA (mRNA) is generated from a DNA gene, that information can be used to identify the original gene sequence and thus measure the ...
Cell & Microbiology
Aug 17, 2022
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662
A high-sugar diet reprograms the taste cells in fruit flies, dulling their sensitivity to sugar and leaving a "molecular memory" on their tongues, according to a University of Michigan study.
Plants & Animals
Nov 11, 2020
1
351
Inserting genetic material into the body to treat diseases caused by gene mutations can work, scientists say—but getting those materials to the right place safely is tricky.
Bio & Medicine
Aug 21, 2020
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222
University of Wisconsin–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination—including a COVID-19 vaccine from ...
Biotechnology
Jul 2, 2020
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284
Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body's extreme reaction to infection.
Bio & Medicine
Jan 6, 2020
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325
Messenger RNA, which can induce cells to produce therapeutic proteins, holds great promise for treating a variety of diseases. The biggest obstacle to this approach so far has been finding safe and efficient ways to deliver ...
Materials Science
Jan 4, 2019
2
775
Messenger ribonucleic acid (mRNA) is a molecule of RNA encoding a chemical "blueprint" for a protein product. mRNA is transcribed from a DNA template, and carries coding information to the sites of protein synthesis: the ribosomes. Here, the nucleic acid polymer is translated into a polymer of amino acids: a protein. In mRNA as in DNA, genetic information is encoded in the sequence of nucleotides arranged into codons consisting of three bases each. Each codon encodes for a specific amino acid, except the stop codons that terminate protein synthesis. This process requires two other types of RNA: transfer RNA (tRNA) mediates recognition of the codon and provides the corresponding amino acid, while ribosomal RNA (rRNA) is the central component of the ribosome's protein manufacturing machinery.
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