Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target these specific proteins. ...
Molecular & Computational biology
Sep 7, 2023
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1
Led by Director Chang Sukbok, scientists from the Center for Catalytic Hydrocarbon Functionalizations within the Institute for Basic Science (IBS) have made a significant advancement in the synthesis of β-lactam scaffolds, ...
Biochemistry
Aug 24, 2023
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101
In a cutting-edge discovery, published in the Journal of the American Chemical Society, Florey scientists have solved a long-standing problem: the need for an affordable, simple way to make peptide-based drugs that hold their ...
Biochemistry
Jul 17, 2023
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61
When a human consumes a pharmaceutical drug, enzymes in the liver break down the substance into metabolites that are water soluble, so the body can more easily excrete them. In some cases, the resulting metabolites may have ...
Biochemistry
Jul 13, 2023
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9
New research from Cardiff University, in collaboration with Astra Zeneca, used artificial intelligence to create microscopic particles that can effectively transport medicines to precisely target and treat diseased cells.
Bio & Medicine
Jun 29, 2023
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34
While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development ...
Analytical Chemistry
May 30, 2023
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136
Diagnosing and treating gastrointestinal tract diseases can be notoriously invasive and time-consuming: blood and stool lab work; biopsies, colonoscopies and endoscopies; and X-rays, CT scans and MRI imaging. But what if ...
Bio & Medicine
May 29, 2023
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71
Before their approval, pharmaceuticals not only have to be tested for their effectiveness and safety, but also for their stability, since they are usually stored in pharmacies and private households for years. To test stability, ...
Analytical Chemistry
May 25, 2023
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33
Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare. Some ...
Cell & Microbiology
May 15, 2023
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29
To develop cancer drugs, researchers often have to make tough trade-offs. Most drugs potent enough to kill tumors also cause unpleasant side effects—and may end up doing more harm than good. Now, researchers and clinicians ...
Bio & Medicine
Apr 26, 2023
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89
