From rare soil microbe, a new antibiotic candidate

Demand for new kinds of antibiotics is surging, as drug-resistant and emerging infections are becoming an increasingly serious global health threat. Researchers are racing to reexamine certain microbes that serve as one of ...

Flow apparatus samples up to 1500 chemical reactions a day

A team of researchers at Pfizer, the pharmaceutical giant, has developed an automated flow chemistry system that is capable of carrying out 1500 reactions over a 24-hour period. In their paper published in the journal Science, ...

Tracking catalytic reactions in microreactors

A pathway to more effective and efficient synthesis of pharmaceutical drugs and other flow reactor chemical products has been opened by a study in which for the first time the catalytic reactivity inside a microreactor was ...

Protein engineers create new biocatalysts

Protein engineers at the California Institute of Technology (Caltech) have tapped into a hidden talent of one of nature's most versatile catalysts. The enzyme cytochrome P450 is nature's premier oxidation catalyst—a protein ...

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