Dr. Cefa Karabag and Dr. Constantino Carlos Reyes-Aldasoro have collaborated with the Francis Crick Institute in preparing and analyzing HeLa cells as part of a research project, documented in the October edition of the PLoS ...
Molecular & Computational biology
Oct 26, 2020
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4
The organization of cells into specific compartments is critical for their function. For instance, by separating the nucleus from the cytoplasm, the nuclear envelope prevents premature translation of immature RNAs.
Cell & Microbiology
Sep 2, 2020
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6
A study has solved a long-standing debate about the transport of essential proteins, implicated in many human diseases, through one of the cell's most complex and sophisticated structures.
Molecular & Computational biology
May 4, 2020
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255
The genetic material of each mammalian cell is safeguarded within the cell's nucleus. In healthy organisms, the usually round-shaped nucleus gets its stability from the nuclear envelope and the nuclear lamina. The latter ...
Cell & Microbiology
Oct 1, 2019
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36
In eukaryotic cells, the nucleus is walled off from the rest of the cell by the nuclear envelope. All transport into and out of the nucleus occurs via cylindrical channels called nuclear pore complexes (NPCs) that penetrate ...
Cell & Microbiology
Jun 12, 2019
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3
Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published November 29 in the open-access ...
Cell & Microbiology
Nov 29, 2018
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16
Scientists at A*STAR have revealed how microtubules, part of a cell's 'skeleton," position the multiple nuclei in muscle cells. Malfunctions in this crucial developmental process are linked to muscular dystrophies, a group ...
Cell & Microbiology
Mar 16, 2018
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4
Like an island nation, the nucleus of a cell has a transportation problem. Evolution has enclosed it with a double membrane, the nuclear envelope, which protects DNA but also cuts it off from the rest of the cell. Nature's ...
Cell & Microbiology
Mar 15, 2018
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126
A team of scientists has revealed an internal clock within live human cells, a finding that creates new opportunities for understanding the building blocks of life and the onset of disease.
General Physics
Sep 11, 2017
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2159
(Phys.org)—Two teams of researchers taking different approaches have successfully mapped and diagramed the nuclear pore complex (NPC)—protein complexes that make up the pores in the nuclear envelope that allow or prevent ...
