Driving force behind cellular 'protein factories' identified
Researchers have identified the driving force behind a cellular process linked to neurodegenerative disorders such as Parkinson's and motor neurone disease.
Researchers have identified the driving force behind a cellular process linked to neurodegenerative disorders such as Parkinson's and motor neurone disease.
Cell & Microbiology
Dec 16, 2020
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130
A remote controlled helicopter has been flown through a series of hoops around a college gymnasium in Minnesota. It sounds like your everyday student project; however, there is one caveat… the helicopter was controlled ...
Engineering
Jun 4, 2013
3
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Recent animal studies have shown that clioquinol - an 80-year old drug once used to treat diarrhea and other gastrointestinal disorders - can reverse the progression of Alzheimer's, Parkinson's and Huntington's diseases. ...
Jan 6, 2009
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When it comes to fighting off invaders, bacteria operate in a remarkably similar way to human cells, possessing the same core machinery required to switch immune pathways on and off, according to new University of Colorado ...
Biochemistry
Feb 9, 2023
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73
A new study from researchers at Karolinska Institutet published in Science Advances show that inactivation of a protein complex that controls gene repression leads to loss of neuronal identity of dopamine-producing cells ...
Cell & Microbiology
Aug 29, 2022
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72
In a finding that has important ramifications for neurodegenerative disorders such as Alzheimer's disease, RIKEN researchers have discovered how three chaperone molecules in yeast cells work together to break up beta-sheet-rich ...
Biochemistry
May 26, 2022
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91
For the first time ever, a Northwestern University-led research team has peered inside a human cell to view a multi-subunit machine responsible for regulating gene expression.
Cell & Microbiology
Mar 11, 2021
1
291
An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress response is a possible ...
Molecular & Computational biology
Mar 11, 2021
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227
A team of Case Western Reserve University researchers has found a way to measure key characteristics of proteins that bind to RNA in cells—a discovery that could improve our understanding of how gene function is disturbed ...
Molecular & Computational biology
Feb 10, 2021
0
62
It shouldn't be any secret that mitochondria can make their own fatty acids. The enzymes mitochondria use to do it were discovered decades ago. Unfortunately, only a few individuals among the biologically literate masses ...
Neurodegenerative disease (Greek νέυρο-, néuro-, "nerval" and Latin dēgenerāre, "to decline" or "to worsen") is a condition in which cells of the brain and spinal cord are lost. The brain and spinal cord are composed of neurons that do different functions such as controlling movements, processing sensory information, and making decisions. Cells of the brain and spinal cord are not readily regenerated en masse, so excessive damage can be devastating. Neurodegenerative diseases result from deterioration of neurons or their myelin sheath which over time will lead to dysfunction and disabilities resulting from this.
Some sources limit the term "degenerative" to conditions primarily affecting gray matter that are not associated with a obvious inciting event.
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