Sugar has been called "evil," "toxic," and "poison." But the body needs sugars, too. Sugar molecules help cells recognize and fight viruses and bacteria, shuttle proteins from cell to cell, and make sure those proteins function. ...
Molecular & Computational biology
Mar 11, 2021
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296
For the first time ever, a Northwestern University-led research team has peered inside a human cell to view a multi-subunit machine responsible for regulating gene expression.
Cell & Microbiology
Mar 11, 2021
1
291
An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress response is a possible ...
Molecular & Computational biology
Mar 11, 2021
0
227
A study led by UT Southwestern has identified a mechanism that controls the activity of proteins known as chaperones, which guide proteins to fold into the right shapes. The findings, published online today in Nature Communications, ...
Molecular & Computational biology
Feb 11, 2021
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174
An international team of researchers led by Michigan State University's Morteza Mahmoudi has developed a new method to better understand how nanomedicines—emerging diagnostics and therapies that are very small yet very ...
Bio & Medicine
Jan 25, 2021
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220
Researchers have identified the driving force behind a cellular process linked to neurodegenerative disorders such as Parkinson's and motor neurone disease.
Cell & Microbiology
Dec 16, 2020
0
130
Cells require a balance among oxidation-reduction reactions, or redox homeostasis. Loss of that balance to create oxidative stress is often associated with neurodegeneration. Less is known about how loss of that balance at ...
Cell & Microbiology
Dec 09, 2020
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2
Researchers at Karolinska Institutet characterize a GTPase involved in ribosome biogenesis in mitochondria. The study, published in Nucleic Acid Research, reveals new details of a complex process that enables mitochondria ...
Biotechnology
Dec 07, 2020
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13
Researchers from the Institut national de la recherche scientifique (INRS) have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.
Nanomaterials
Nov 09, 2020
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14
The transport of amino acids and other molecules across the cell's membrane plays a crucial role in the metabolism of cells and, therefore, in human health. Current research hints that cancer, cystic fibrosis, aminoacidurias ...
Biochemistry
Oct 06, 2020
0
6
Neurodegenerative disease (Greek νέυρο-, néuro-, "nerval" and Latin dēgenerāre, "to decline" or "to worsen") is a condition in which cells of the brain and spinal cord are lost. The brain and spinal cord are composed of neurons that do different functions such as controlling movements, processing sensory information, and making decisions. Cells of the brain and spinal cord are not readily regenerated en masse, so excessive damage can be devastating. Neurodegenerative diseases result from deterioration of neurons or their myelin sheath which over time will lead to dysfunction and disabilities resulting from this.
Some sources limit the term "degenerative" to conditions primarily affecting gray matter that are not associated with a obvious inciting event.
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