Related topics: cells · breast cancer · cancer cells · protein

Watch how cells squeeze through channels

Observations of cells moving through small channels shed new light on cell migration in 3-D environments, researchers report October 6 in Biophysical Journal. The findings also reveal how cancer cells may penetrate tissues ...

Study sheds new light on cell migration

The 3-D structure of the ELMO / DOCK2 complex, an important molecular machine that plays a crucial role in cell migration in the body, is now better understood thanks to new research by scientists in Montreal and the United ...

A new tool to map the flow of info within living cells

How do cells move? Why do they move? Why do some cancer cells move slowly while others move quickly, causing a cancerous tumor to metastasize and become much more difficult to treat effectively? The answers are not as simple ...

Distinct roles for myosins in 'tuning' cell shape for division

Mechanical properties of the cell cortex—a thin network of actin filaments under the cell membrane—regulate shape changes during cell division, cell migration and tissue development. Two forms of the molecular motor myosin-II ...

How cells muster and march out

Many of the cell types in our bodies are constantly on the move. LMU physicists have developed a mathematical model that describes, for the first time, how single-cell migration can coalesce into coordinated movements of ...

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Cell migration

Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing and immune responses all require the orchestrated movement of cells in particular directions to specific locations. Errors during this process have serious consequences, including mental retardation, vascular disease, tumor formation and metastasis. An understanding of the mechanism by which cells migrate may lead to the development of novel therapeutic strategies for controlling , for example, invasive tumour cells. Cells often migrate in response to, and towards, specific external signals, a process called chemotaxis.

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