Related topics: cells · breast cancer · cancer cells · protein

Complex patterns: Building a bridge from the large to the small

For many processes important for life such as cell division, cell migration, and the development of organs, the spatially and temporally correct formation of biological patterns is essential. To understand these processes, ...

Breakthrough in study of how epithelial cells become cancerous

Epithelial cells, which line the surfaces and organs of the body, can protect themselves against cancer by removing unhealthy or abnormal cells through a mechanism known as "apical extrusion," where the damaged cells are ...

Dividing walls: How immune cells enter tissue

To get to the places where they are needed, immune cells not only squeeze through tiny pores. They even overcome wall-like barriers of tightly packed cells. Researchers at the Institute of Science and Technology Austria (ISTA) ...

Cytoskeletal proteins interact to form intracellular networks

Investigators have discovered that two cytoskeletal proteins which were previously thought to function independently actually interact and form cytoskeletal networks within the cell surface, according to findings published ...

Using nanofibers to stop brain tumor cells from spreading

Brain cancer is difficult to contain and is often resistant to conventional treatment methods. Predicting tumor cell behavior requires a better understanding of their invasion mechanism. Now, researchers from University of ...

Strengthened microtubules aid cell migration

Migrating cells use stiffened microtubules to push through tissue barriers, seeking out weak points in tissue, according to a Northwestern Medicine study published in Cell Reports.

Protein's 'silent code' affects how cells move

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% ...

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Cell migration

Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing and immune responses all require the orchestrated movement of cells in particular directions to specific locations. Errors during this process have serious consequences, including mental retardation, vascular disease, tumor formation and metastasis. An understanding of the mechanism by which cells migrate may lead to the development of novel therapeutic strategies for controlling , for example, invasive tumour cells. Cells often migrate in response to, and towards, specific external signals, a process called chemotaxis.

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