Related topics: cells · breast cancer · cancer cells · protein

Strengthened microtubules aid cell migration

Migrating cells use stiffened microtubules to push through tissue barriers, seeking out weak points in tissue, according to a Northwestern Medicine study published in Cell Reports.

Protein's 'silent code' affects how cells move

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% ...

How cells recycle the machinery that drives their motility?

Research groups at University of Helsinki and Institut Jacques Monod, Paris, discovered a new molecular mechanism that promotes cell migration. The discovery sheds light on the mechanisms that drive uncontrolled movement ...

Researchers find how cells move while avoiding adhesion

Cell velocity, or how fast a cell moves, is known to depend on how sticky the surface is beneath it, but the precise mechanisms of this relationship have remained elusive for decades. Now, researchers from the Max Delbrück ...

Watch how cells squeeze through channels

Observations of cells moving through small channels shed new light on cell migration in 3-D environments, researchers report October 6 in Biophysical Journal. The findings also reveal how cancer cells may penetrate tissues ...

Study sheds new light on cell migration

The 3-D structure of the ELMO / DOCK2 complex, an important molecular machine that plays a crucial role in cell migration in the body, is now better understood thanks to new research by scientists in Montreal and the United ...

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Cell migration

Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing and immune responses all require the orchestrated movement of cells in particular directions to specific locations. Errors during this process have serious consequences, including mental retardation, vascular disease, tumor formation and metastasis. An understanding of the mechanism by which cells migrate may lead to the development of novel therapeutic strategies for controlling , for example, invasive tumour cells. Cells often migrate in response to, and towards, specific external signals, a process called chemotaxis.

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