New mitochondrially-derived peptides show what they can do
Genetic switch regulates transcription and replication in human mitochondria
Scientists re-create what may be life's first spark
Scientists in a lab used a powerful laser to re-create what might have been the original spark of life on Earth.
World's first artificial enzymes created using synthetic biology
(Phys.org)—Medical Research Council (MRC) scientists have created the world's first enzymes made from artificial genetic material. Their synthetic enzymes, which are made from molecules that do not occur ...
Scientists make enzyme that could help explain origins of life
Mimicking natural evolution in a test tube, scientists at The Scripps Research Institute (TSRI) have devised an enzyme with a unique property that might have been crucial to the origin of life on Earth.
Scientists resurrect 700-year-old viruses
Human cells' protein factory has an alternate operating manual
Working with a gene that plays a critical role in HIV infection, University of Maryland researchers have discovered that some human genes have an alternate set of operating instructions written into their ...
RNA carried by new nanoparticles can silence genes in many organs, could be deployed to treat cancer
RNA interference (RNAi), a technique that can turn off specific genes inside living cells, holds great potential for treating many diseases caused by malfunctioning genes. However, it has been difficult for ...
Vast gene-expression map yields neurological and environmental stress insights
(Phys.org) —A consortium led by scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) has conducted the largest survey yet of how information encoded in an ...
Advanced techniques yield new insights into ribosome self-assembly
Ribosomes, the cellular machines that build proteins, are themselves made up of dozens of proteins and a few looping strands of RNA. A new study, reported in the journal Nature, offers new clues about how th ...
Better RNA interference, inspired by nature: New nanoparticles offer best-ever gene silencing
Inspired by tiny particles that carry cholesterol through the body, MIT chemical engineers have designed nanoparticles that can deliver snippets of genetic material that turn off disease-causing genes.
Crowdsourced RNA designs outperform computer algorithms
An enthusiastic group of non-experts, working through an online interface and receiving feedback from lab experiments, has produced designs for RNA molecules that are consistently more successful than those generated by the ...
Error-correction strategy allows precise measurement of transcriptome in single cells
Howard Hughes Medical Institute (HHMI) scientists have devised a method of visualizing RNA molecules inside cells so that the identity, location, and abundance of more than 1,000 different RNA species can ...
Breakthrough finds molecules that block previously 'undruggable' protein tied to cancer
A team of scientists at the University of Kansas has pinpointed six chemical compounds that thwart HuR, an "oncoprotein" that binds to RNA and promotes tumor growth.