Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine. Guiding iPSCs toward a target cell line has garnered much attention, but the process ...
Cell & Microbiology
Oct 10, 2023
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1
During the first hours of an embryo's development, specialized molecules called pioneer transcription factors unravel parts of its DNA to activate the encoded genes. Which gene is activated and when has to follow a set schedule ...
Cell & Microbiology
Sep 28, 2023
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The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some extent in mice, human ...
Biotechnology
Sep 21, 2023
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A research team headed by Prof. Jacob Hanna at the Weizmann Institute of Science has created complete models of human embryos from stem cells cultured in the lab—and managed to grow them outside the womb up to day 14. As ...
Cell & Microbiology
Sep 6, 2023
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In-vitro culture of biological cells plays an important role in advancing biological research. However, currently available cell culture materials have significant drawbacks. Many of them are derived from animal sources, ...
Bio & Medicine
Aug 15, 2023
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59
There are several parallel projects running across the world to save the northern white rhinoceros (Ceratotherium simum simum), one of Africa's captivating and iconic wildlife species. With the death of last male in 2018 ...
Plants & Animals
Aug 14, 2023
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1
Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a "black box" of human development. This is because human embryos are typically not cultured for ...
Cell & Microbiology
Jul 20, 2023
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45
As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these signaling molecules guide ...
Cell & Microbiology
Jul 17, 2023
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34
In a groundbreaking study, researchers have unlocked a new frontier in the fight against aging and age-related diseases. The study, conducted by a team of scientists at Harvard Medical School, has published the first chemical ...
Cell & Microbiology
Jul 13, 2023
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761
In humans, pregnancy lasts around nine months. In mice, only 20 days, and in rhinoceroses, as long as 17 months. Although many mammalian species go through the same stages during embryo development, the speed of development ...
Plants & Animals
Jun 20, 2023
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