In eukaryotic cells, the nucleus is walled off from the rest of the cell by the nuclear envelope. All transport into and out of the nucleus occurs via cylindrical channels called nuclear pore complexes (NPCs) that penetrate ...
Cell & Microbiology
Jun 12, 2019
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Standing guard between a cell's nucleus and its main chamber, called the cytoplasm, are thousands of behemoth protein structures called nuclear pore complexes, or NPCs. NPCs are like the bouncers of a cell's nucleus, tightly ...
Cell & Microbiology
Jun 13, 2018
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119
Cells can avoid "data breaches" when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert ...
Biochemistry
Mar 27, 2018
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183
Like an island nation, the nucleus of a cell has a transportation problem. Evolution has enclosed it with a double membrane, the nuclear envelope, which protects DNA but also cuts it off from the rest of the cell. Nature's ...
Cell & Microbiology
Mar 15, 2018
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126
All creatures of the animal kingdom share one thing: the nuclear membrane. Wrapping the genetic core of the cell, this membrane, together with all the attached proteins, plays a vital role in biological functions. Despite ...
Cell & Microbiology
Sep 8, 2017
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Nuclear pore complexes are tiny channels where the exchange of substances between the cell nucleus and the cytoplasm takes place. Scientists at the University of Basel report on startling new research that might overturn ...
Cell & Microbiology
Sep 4, 2017
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One of the key reasons for cancer mortality is the highly invasive behaviour of cancer cells, which is often due to aggressive metastasis. Metastasis is facilitated by various growth factors and cytokines secreted from cells ...
Bio & Medicine
Jun 30, 2017
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Cells secure DNA within their nuclei like a secret code stashed in a vault. However, the tightly controlled borders of the nucleus create a challenge: In order for the cell to produce essential proteins, messages derived ...
Cell & Microbiology
Nov 11, 2016
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701
Using an ultra fast-scanning atomic force microscope, a team of researchers from the University of Basel has filmed "living" nuclear pore complexes at work for the first time. Nuclear pores are molecular machines that control ...
Bio & Medicine
May 2, 2016
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It was a 3D puzzle with over 1000 pieces, with only a rather fuzzy outline as a guide. But scientists at EMBL have now put enough pieces in place to see the big picture. In a study published today in Science, they present ...
Cell & Microbiology
Apr 15, 2016
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