(Phys.org)—Two teams of researchers taking different approaches have successfully mapped and diagramed the nuclear pore complex (NPC)—protein complexes that make up the pores in the nuclear envelope that allow or prevent ...
Caltech scientists have produced the most detailed map yet of the massive protein machine that controls access to the DNA-containing heart of the cell.
Biochemistry
Apr 15, 2016
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2157
Long before animals evolved from sponges, and before plants evolved out of algae, there was a pivotal event that allowed complex, multicellular organisms to arise: the development of the nucleus in single-celled organisms. ...
Evolution
Mar 21, 2016
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16
(Phys.org)—If asked to describe the differences between humans and frogs, a child might say that one hops and rib-its while the other walks and talks. If we ask that same child how to build a frog, they will probably need ...
Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have uncovered new clues to how a molecular machine inside the cell acts as a gatekeeper, allowing some molecules to enter ...
Cell & Microbiology
Nov 6, 2015
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81
A cell does everything it can to protect its nucleus, where precious genetic information is stored. That includes controlling the movement of molecules in and out using gateways called nuclear pore complexes (NPCs).
Cell & Microbiology
Sep 18, 2015
2
146
Not just anything is allowed to enter the nucleus, the heart of eukaryotic cells where, among other things, genetic information is stored. A double membrane, called the nuclear envelope, serves as a wall, protecting the contents ...
Biochemistry
Aug 27, 2015
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3197
U of T researchers have discovered how severely damaged DNA is transported within a cell and how it is repaired.
Cell & Microbiology
Jul 24, 2015
8
39
Cells have devised many structures for transporting molecular cargo across their protective borders, but the nuclear pore complex, with its flower-like, eight-fold symmetry, stands out. Monstrously large by cellular standards, ...
Cell & Microbiology
Jun 5, 2015
1
885
Facing a challenge akin to solving a 1,000-piece jigsaw puzzle while blindfolded—and without touching the pieces—many structural biochemists thought it would be impossible to determine the atomic structure of a massive ...
Cell & Microbiology
Feb 13, 2015
0
37
