A team at the Max Dellbruck Center has answered a question that has puzzled scientists for some 40 years. In the journal Cell, the group explains how cells are able to switch on completely different signaling pathways using ...
Cell & Microbiology
Aug 25, 2020
0
75
Researchers from Aarhus University challenge one of the cornerstones of biochemistry, the Michaelis-Menten equation. They show that many enzymes in signaling pathways are independent of substrate concentration, because the ...
Biochemistry
Aug 20, 2020
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375
PIM kinases are enzymes that promote metastatic growth and spread of cancer cells. Researchers from the University of Turku, Finland, have obtained new information on how PIM kinases enhance cancer cell motility by regulating ...
Cell & Microbiology
Aug 19, 2020
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5
Cellular signal transmission is not only optimized for precision—it also includes a cost cap. The relationship between information and energy, a concept well established in physics and engineering, is likely to fundamentally ...
Cell & Microbiology
Jul 20, 2020
0
126
A team of researchers affiliated with several institutions in South Korea has found that stimulating production of a certain enzyme in roundworms can increase their lifespan. In their paper published in the journal Science ...
Leiden chemists have developed a new technique with which they can determine the role of kinases—a group of proteins—in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer ...
Biotechnology
Jun 29, 2020
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21
A research team led by Dr. Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong (HKU), in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the ...
Cell & Microbiology
Jun 16, 2020
0
3
Plant biologists have long sought a deeper understanding of foundational processes involving kinases, enzymes that catalyze key biological activities in proteins. Analyzing the processes underlying kinases in plants takes ...
Cell & Microbiology
Jun 1, 2020
0
212
Recently, a research team led by Dr. Liu Qingsong and Dr. Liu Jing from High Magnetic Field Laboratory of the Chinese Academy of Sciences has discovered a novel FLT3-ITD mutation-selective kinase inhibitor CHMFL-FLT3-362, ...
Molecular & Computational biology
May 20, 2020
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3
Phytohormone ethylene plays essential roles in plant growth and development and response to stresses. In dicot Arabidopsis, the ethylene signaling pathway has been well-characterized. Ethylene signal is perceived and transduced ...
Plants & Animals
Mar 9, 2020
0
5
