Related topics: cancer cells

Resetting the biological clock by flipping a switch

The biological clock is present in almost all cells of an organism. As more and more evidence emerges that clocks in certain organs could be out of sync, there is a need to investigate and reset these clocks locally. Scientists ...

Breakthrough study shows how plants sense the world

Plants lack eyes and ears, but they can still see, hear, smell and respond to environmental cues and dangers—especially to virulent pathogens. They do this with the aid of hundreds of membrane proteins that can sense microbes ...

Scientists blueprint tiny cellular 'nanomachine'

Scientists have drawn up molecular blueprints of a tiny cellular 'nanomachine', whose evolution is an extraordinary feat of nature, by using one of the brightest X-ray sources on Earth.

To starve a tumor

(PhysOrg.com) -- Since the 1920s, scientists have known that cancer cells generate energy differently than normal cells, a phenomenon dubbed the 'Warburg effect' after its discoverer, German biochemist Otto Warburg. However, ...

Receptor tyrosine kinases control mechanosensors

Researchers at the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have identified a role of receptor tyrosine kinases in the regulation of the cellular mechanosensory machinery, which has relevance ...

Architecture of mTOR protein complex solved

For a long time it has been known that the protein TOR - Target of Rapamycin - controls cell growth and is involved in the development of diseases such as cancer and diabetes. Researchers at the University of Basel's Biozentrum ...

Skin cancer mystery revealed in yin and yang protein

It starts off small, just a skin blemish. The most common moles stay just that way—harmless clusters of skin cells called melanocytes, which give us pigment. In rare cases, what begins as a mole can turn into melanoma, ...

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Kinase

In chemistry and biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, a process referred to as phosphorylation. Kinases are part of the larger family of phosphotransferases. Kinases are not to be confused with phosphorylases, which carry out phosphorolysis, the breaking of a bond using an inorganic phosphate group; or with phosphatases, which remove phosphate groups.

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