Chromatin regulation enables generation of diverse antibodies

We need a variety of antibody types to help fight off invading foreign pathogens and our genome is exquisitely tuned to produce them to meet emerging needs. A new study finds that not just our DNA, but its configuration and ...

How organ functions were shaped over the course of evolution

A large-scale study conducted by molecular biologists from Heidelberg University has yielded groundbreaking new insights into the evolution and regulation of gene expression in mammalian organs. The scientists investigated ...

European and American maize: Same same, but different

German researchers decoded the European maize genome. In comparison to North American maize lines, they discovered variations that underlie phenotypic differences and may also contribute to the heterosis effect. A better ...

Desert algae shed light on desiccation tolerance in green plants

Deserts of the U.S. Southwest are extreme habitats for most plants, but, remarkably, microscopic green algae live there that are extraordinarily tolerant of dehydration. These tiny green algae (many just a few microns in ...

A genome-scale map of DNA methylation kinetics

While the first genome-wide DNA methylation map in mammalian cells was established over 10 years ago, such maps only provide snapshots and do not inform about the actual dynamics of this epigenetic mark. Researchers from ...

New technology will show how RNA regulates gene activity

The discovery of a huge number of long non-protein coding RNAs, aka lncRNAs, in the mammalian genome was a major surprise of the recent large-scale genomics projects. An international team including a bioinformatician from ...

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