News tagged with gene regulation
New details about gene regulation explained
(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase ...
May 21, 2012 |
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Scientists discover multiple gene switches in Salmonella, offer new ways to curb infection
Scientists have discovered multiple gene switches in Salmonella that offer new ways to curb human infection. The discovery of the mechanisms of gene regulation could lead to the development of antibiotics to reduce the le ...
Apr 23, 2012 |
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History is key factor in plant disease, study finds
(Phys.org) -- The virulence of plant-borne diseases depends on not just the particular strain of a pathogen, but on where the pathogen has been before landing in its host, according to a new study from researchers ...
Apr 19, 2012 |
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Scientists find a key to growth differences between species
The tiny, little-noticed jewel wasp may provide some answers as to how different species differ in size and shape. And that could lead to a better understanding of cell growth regulation, as well as the underlying ...
Feb 23, 2012 |
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Study provides new insights into an ancient mechanism of mammalian evolution
A team of geneticists and computational biologists in the UK today reveal how an ancient mechanism is involved in gene control and continues to drive genome evolution. The new study is published in the journal ...
Jan 12, 2012 |
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The machinery of chromatin regulation
Ten years after the human genome was first published, researchers have found new clues into the machinery that influences gene function. The team, led by Bradley Bernstein, an associate professor of pathology ...
Dec 23, 2011 |
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Transcriptional elongation control takes on new dimensions
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in ...
Dec 22, 2011 |
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Dundee researchers make gene breakthrough
Researchers at the University of Dundee have made a significant breakthrough in understanding how human cells decode genes important for cell growth and multiplication.
Sep 16, 2011 |
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'TF beacons' may light path to new cancer tests and drugs
Scientists are reporting development of a long-sought new way to detect the activity of proteins that bind to the DNA in genes, often controlling the activity of genes in ways that make cells do everything ...
Sep 07, 2011 |
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Sequencing platform provides powerful tool for identifying subtle changes in gene expression
In a truly challenging task, the FANTOM5 Consortium, an international collaboration headed by scientists at the RIKEN Omics Science Center in Yokohama, Japan, is striving to profile the regulation of gene ...
Sep 02, 2011 |
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Three periods of innovation in gene regulation occurred during the evolution of vertebrate animals: study
Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...
Aug 18, 2011 |
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Novel DNA sequencer for MDC's systems biology
The Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a ...
Jul 15, 2011 |
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Researchers identify new mechanism used by cells to reverse silenced genes
Scientists at Fox Chase Cancer Center have discovered a new mechanism used by cells in the body to turn on silenced genes. This process is critical in preventing the development of cancer -- suggesting the possibility of ...
Jun 30, 2011 |
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Extensive protein interaction network controls gene regulation
The genes of a cell are like the 88 keys of a piano. To play chords and music, however, the keys must be activated in exact combinations by a pianist's hands. Those hands represent the coregulators of a cell that simultaneously ...
May 26, 2011 |
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Discovery in liver cancer cells provides new target for drugs
Researchers at Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine (VIMM) have discovered a novel mechanism in gene regulation that contributes to the development of a form of liver ...
Mar 22, 2011 |
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Regulation of gene expression
Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.
Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.
Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.
Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.
For more information about Regulation of gene expression, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
