Which came first the head or the brain?
New key to organism complexity identified: Critical transcription factor co-exists in two distinct states
Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate ...
Jan 17, 2013
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Study turns parasite invasion theory on its head
Current thinking on how the Toxoplasma gondii parasite invades its host is incorrect, according to a study published today in Nature Methods describing a new technique to knock out genes. The findings coul ...
Dec 23, 2012
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Scientists cut through data noise of high-throughput DNA sequencing with mathematical technique
(Phys.org) —Scientists at A*STAR's Genome Institute of Singapore (GIS) have developed a revolutionary method to quickly cut through noise and generate a unified and simplified analysis of high-throughput biological data ...
Jun 17, 2013
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Duck genome provides new insight into fighting bird flu
The duck genome consortium, consisted of scientists from China Agricultural University, BGI, University of Edinburgh and other institutes has completed the genome sequencing and analysis of the duck (Anas pl ...
Jun 09, 2013
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Human Argonaute proteins: To slice or not to slice?
What makes one Argonaute a slicer and another one not? Human Argonaute proteins are key players in the gene regulation process known as RNA interference, RNAi. Professor Joshua-Tor's group of Cold Spring Harbor Laboratory ...
Jun 06, 2013
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DNA gridlock: Cells undo glitches to prevent mutations
Roughly six feet of DNA are packed into every human cell, so it is not surprising that our genetic material occasionally folds into odd shapes such as hairpins, crosses and clover leafs. But these structures ...
Jun 03, 2013
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KISS ME DEADLY proteins may help improve crop yields
Dartmouth College researchers have identified a new regulator for plant hormone signaling—the KISS ME DEADLY family of proteins (KMDs) – that may help to improve production of fruits, vegetables and grains.
May 27, 2013
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Team finds how a key enzyme of the spliceosome exerts its controlling function
To sustain life, processes in biological cells have to be strictly controlled both in time and in space. Research workers at the Max Planck Institute for Biophysical Chemistry in Göttingen and Freie Universität ...
May 27, 2013
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Salk researchers chart epigenomics of stem cells that mimic early human development
Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions ...
May 09, 2013
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Lucky bacteria strike it rich during formation of treatment-resistant colonies
In biology, we often think of natural selection and survival of the fittest. What about survival of the luckiest? Like pioneers in search of a better life, bacteria on a surface wander around and often organize into highly ...
May 08, 2013
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It slices, it dices, it silences: ADAR1 as gene-silencing modular RNA multitool
RNA, once considered a bit player in the grand scheme by which genes encode protein, is increasingly seen to have a major role in human genetics. In a study presented in the April 25 issue of the journal Cell, researchers from T ...
May 01, 2013
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Team discovers how a protein finds its way
(Phys.org) —Proteins, the workhorses of the body, can have more than one function, but they often need to be very specific in their action or they create cellular havoc, possibly leading to disease.
Apr 29, 2013
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Threaded through a pore: Single-molecule detection of hydroxymethylcytosine in DNA
(Phys.org) —Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn't. In the journal Angewandte Chemie, a British team has now introduced a new ...
Apr 25, 2013
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Cell on a chip reveals protein behavior
A simplified version of an artificial cell produces functional proteins and even sorts them.
Mar 18, 2013
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