Despite huge advances in our understanding of COVID-19 over the past four years, the disease is still very much among us—and there remains a lot to learn.
Cell & Microbiology
Apr 24, 2024
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28
A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases, enzymes commonly used ...
Biotechnology
Apr 23, 2024
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14
Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.
Cell & Microbiology
Apr 22, 2024
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19
The beginning of life on Earth and its evolution over billions of years continue to intrigue researchers worldwide. The central dogma or the directional flow of genetic information from a deoxyribose nucleic acid (DNA) template ...
Molecular & Computational biology
Apr 18, 2024
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141
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development ...
Cell & Microbiology
Apr 18, 2024
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20
The technology used to sequence SARS-CoV-2 at record speed early in the COVID-19 pandemic has been successfully tested as a technique to monitor arboviruses and diseases transmitted mainly by mosquitoes.
Biotechnology
Apr 17, 2024
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8
The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate.
Biotechnology
Apr 12, 2024
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99
Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's ...
Biochemistry
Apr 10, 2024
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65
RNA—in the form of messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA)—transforms the genome coded by DNA into proteins that form the backbone of all cellular functions. However, biochemical modifications ...
Cell & Microbiology
Apr 8, 2024
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25
Researchers at the University of Colorado Anschutz Medical Campus have discovered a mechanism by which a bacterial virus undermines the virulence of Salmonella, allowing the host a chance to rehabilitate.
Cell & Microbiology
Apr 5, 2024
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31
