(Phys.org) —Researchers hope to hijack a natural process called RNA interference to block the production of proteins linked to disease and treat medical conditions for which conventional drugs do not work, including cancer, ...
Biochemistry
Sep 27, 2013
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(Phys.org) —Last month, researchers reported the creation of the first primitive brain-like structures made from human stem cells. To create the complex morphology of these cerebral organoids, cells within a proliferating ...
By creating a powerful new gene regulation system called CRISPR-on, Whitehead Institute researchers now have the ability to increase the expression of multiple genes simultaneously and precisely manipulate each gene's expression ...
Biotechnology
Aug 27, 2013
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On July 25th JoVE, the Journal of Visualized Experiments will publish a new technique that will help scientists better understand the genes that govern food-related behavior in honey bees. The impact of this study could take ...
Plants & Animals
Jul 25, 2013
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Standard toxicity testing is inadequate to assess the safety of a new technology with potential for creating pesticides and genetically modifying crops, according to a Forum article published in the August issue of BioScience. ...
Cell & Microbiology
Jul 16, 2013
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Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which ...
Bio & Medicine
Jul 9, 2013
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Nanoparticles that deliver short strands of RNA offer a way to treat cancer and other diseases by shutting off malfunctioning genes. Although this approach has shown some promise, scientists are still not sure exactly what ...
Bio & Medicine
Jun 24, 2013
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What makes one Argonaute a slicer and another one not? Human Argonaute proteins are key players in the gene regulation process known as RNA interference, RNAi. Professor Joshua-Tor's group of Cold Spring Harbor Laboratory ...
Cell & Microbiology
Jun 6, 2013
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Many proteins undergo extensive modification after being synthesized, particularly those that are secreted or embedded in the cell membrane. This is achieved within the Golgi apparatus (see image), a cellular organelle consisting ...
Cell & Microbiology
Apr 24, 2013
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(Phys.org) —Every available cancer drug is susceptible to resistance, according to Mansoor Amiji, Distinguished Professor and chair of the Department of Pharmaceutical Sciences. Tumors grow more quickly than blood vessels, ...
Bio & Medicine
Mar 19, 2013
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