Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery—it is extremely ...
Biotechnology
Nov 17, 2014
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The application of a new, precise way to turn genes on and off within cells, described online October 9, 2014 in two articles in the journal Cell, is likely to lead to a better understanding of diseases and possibly to new ...
Cell & Microbiology
Oct 14, 2014
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A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA, the molecule that translates DNA's genetic instructions into the production of proteins. A team of researchers with Berkeley ...
Cell & Microbiology
Oct 3, 2014
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MIT engineers have devised a way to rapidly test hundreds of different drug-delivery vehicles in living animals, making it easier to discover promising new ways to deliver a class of drugs called biologics, which includes ...
Biotechnology
Sep 30, 2014
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During the winter of 1944, the Nazis blocked food supplies to the western Netherlands, creating a period of widespread famine and devastation. The impact of starvation on expectant mothers produced one of the first known ...
Cell & Microbiology
Jul 31, 2014
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Macromolecular complexes composed of self-assembling proteins and nucleic acids hold promise for a wide range of applications, including drug delivery, sensing and molecular electronics. Scientists have developed a broad ...
Biochemistry
Jul 4, 2014
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RNA interference (RNAi), a technique that can turn off specific genes inside living cells, holds great potential for treating many diseases caused by malfunctioning genes. However, it has been difficult for scientists to ...
Bio & Medicine
May 12, 2014
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Inspired by tiny particles that carry cholesterol through the body, MIT chemical engineers have designed nanoparticles that can deliver snippets of genetic material that turn off disease-causing genes.
Bio & Medicine
Feb 11, 2014
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The team of Johannes Zuber at the IMP in Vienna, Austria, managed to overcome remaining key limitations of RNA interference (RNAi) - a unique method to specifically shut off genes. By using an optimized design, the scientists ...
Cell & Microbiology
Dec 13, 2013
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A team led by Chris Sullivan, a professor of molecular biosciences at The University of Texas at Austin, has provided the first positive evidence that RNA interference (RNAi), a biological process in which small RNA molecules ...
Cell & Microbiology
Oct 15, 2013
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