Junk DNA in birds may hold key to safe, efficient gene therapy

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes ...

Precise transcript targeting by CRISPR-Csm complexes

Mammalian cells are inherently complex due to subcellular compartments, thereby making the process of robust transcript targeting of nucleic acids somewhat challenging in the molecular biology lab. In a recent report now ...

Genetically altered daddy longlegs have short legs

A team of researchers from the University of Wisconsin, the Smithsonian Institution's National Museum of Natural History, and Western Connecticut State University, has assembled the first draft genome of Phalangium opilio—the ...

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