As molecular biologists at Boston University and as husband and wife, Ruslan Afasizhev and Inna Afasizheva have worked together for decades. Together, they have published dozens of papers on the mechanics of mitochondrial ...
Molecular & Computational biology
Jul 19, 2023
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81
Membraneless organelles (MLOs), also known as "biomolecular condensates," are formed by the biological process of liquid-liquid phase separation (LLPS). MLOs are highly dynamic bodies containing proteins and nucleic acids.
Cell & Microbiology
Jul 18, 2023
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12
When bacteria are attacked by a virus, they can defend themselves with a mechanism that fends off the genetic material introduced by the intruder. The key is CRISPR-Cas protein complexes. It is only in the last decade that ...
Biotechnology
Jul 13, 2023
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59
Cellular identity is defined by gene activity that drives intercellular communication and is pivotal to understand mechanisms underlying multicellular organisms. In a new report Abbas Ghaddar and a research team in biology, ...
Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.
Biotechnology
Jul 3, 2023
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4643
CRISPR gene editing is a breakthrough that has been used to treat diseases such as sickle cell anemia, leukemia and genetic disorders, but it has challenges that limit its broad utility.
Biotechnology
Jun 29, 2023
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15
RNA, an essential biomolecule for life, has been used in environmental applications including monitoring microbial communities, developing pesticides, and quantifying the abundance of pathogenic viruses, such as SARS-CoV-2, ...
Biochemistry
Jun 27, 2023
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82
People with weakened immune systems are at constant risk of infection. Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections ...
Cell & Microbiology
Jun 14, 2023
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73
Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy. The groups of Marino Zerial, Max Planck Institute ...
Cell & Microbiology
Jun 2, 2023
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116
Researchers at Karolinska Institutet in Sweden have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes. The findings are presented in the journal Nature Microbiology ...
Cell & Microbiology
May 22, 2023
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160
