Scientists from the Institute of Organic Chemistry and Biochemistry in Prague have deciphered the structure of the protein methyltransferase from the monkeypox virus. It is with the help of this protein that the virus escapes ...
Biochemistry
Apr 28, 2023
0
26
Single-cell RNA-sequencing (scRNA-seq) technologies offer the opportunity to understand regulatory mechanisms at single-cell resolution. Gene regulatory networks (GRNs) provide a crucial blueprint of regulatory mechanisms ...
Molecular & Computational biology
Apr 27, 2023
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2
Ribonucleic acid (RNA) folds into complex structures, which allow it to interact specifically with other molecules in the cell. In HIV-1, minute differences in RNA folding can be crucial in determining whether viral RNA is ...
Bio & Medicine
Apr 27, 2023
0
24
In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes. This marked the discovery of microRNAs (miRNAs), which are now ...
Cell & Microbiology
Apr 24, 2023
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3
A team led by Prof. Zhang Kaiming from the University of Science and Technology (USTC) solved six conformations in the second-step self-splicing of Tetrahymena ribozyme using cryogenic electron microscopy (cryo-EM), revealing ...
Biochemistry
Apr 10, 2023
0
14
Scientists at St. Jude Children's Research Hospital revealed that human ribosomes decode messenger RNA (mRNA) 10 times slower than bacterial ribosomes, but do so more accurately. The study, published today in Nature, used ...
Cell & Microbiology
Apr 5, 2023
0
52
Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide. Looking to contribute a solution to this growing problem, ...
Cell & Microbiology
Mar 31, 2023
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75
Scientists have discovered a new way to suppress mutations that lead to a wide range of genetic disorders.
Biotechnology
Mar 9, 2023
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75
Life began on Earth more than 3.5 billion years ago, but the history of humans and other vertebrates accounts for only a fraction of this timescale. Chordates (a group that includes vertebrates) and echinoderms (like starfish ...
Evolution
Feb 23, 2023
0
290
University of Chicago scientists have discovered a new wrinkle in our understanding of how our genes work. The team, led by Chuan He, the UChicago John T. Wilson Distinguished Service Professor of Chemistry, Biochemistry ...
Molecular & Computational biology
Feb 13, 2023
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